Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5154
MIM: 173430
HGNC: 8799
Ensembl: ENSG00000197461
Variants:
dbSNP: 5154
ClinVar: 5154
TCGA: ENSG00000197461
COSMIC: PDGFA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000197461 | ENST00000354513 | P04085 |
| ENSG00000197461 | ENST00000400761 | H7BYW6 |
| ENSG00000197461 | ENST00000402802 | P04085 |
| ENSG00000197461 | ENST00000405692 | A0A0A0MSC4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36306470 | 2023 | PDGF-AA activates AKT and ERK signaling for testicular interstitial Leydig cell growth via primary cilia. | 1 |
| 36608914 | 2023 | Molecular profile and peripheral markers of neurodegeneration in patients with Niemann-Pick type C: Decrease in Plasminogen Activator Inhibitor type 1 and Platelet-Derived Growth Factor type AA. | 1 |
| 36306470 | 2023 | PDGF-AA activates AKT and ERK signaling for testicular interstitial Leydig cell growth via primary cilia. | 1 |
| 36608914 | 2023 | Molecular profile and peripheral markers of neurodegeneration in patients with Niemann-Pick type C: Decrease in Plasminogen Activator Inhibitor type 1 and Platelet-Derived Growth Factor type AA. | 1 |
| 35105853 | 2022 | EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic target in glioblastoma. | 11 |
| 35241778 | 2022 | PDGF regulates guanylate cyclase expression and cGMP signaling in vascular smooth muscle. | 3 |
| 35716012 | 2022 | PDGFA-associated protein 1 is a novel target of c-Myc and contributes to colorectal cancer initiation and progression. | 9 |
| 35105853 | 2022 | EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic target in glioblastoma. | 11 |
| 35241778 | 2022 | PDGF regulates guanylate cyclase expression and cGMP signaling in vascular smooth muscle. | 3 |
| 35716012 | 2022 | PDGFA-associated protein 1 is a novel target of c-Myc and contributes to colorectal cancer initiation and progression. | 9 |
| 33760132 | 2021 | HaCaT‑conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF‑AA prevents the dedifferentiation of dermal papilla cells in vitro. | 4 |
| 33892919 | 2021 | Platelet-Derived Growth Factor Predicts Vulnerable Plaque in Patients with Non-ST Elevation Acute Coronary Syndrome. | 2 |
| 34011067 | 2021 | High expression of PDGFA predicts poor prognosis of esophageal squamous cell carcinoma. | 9 |
| 34885714 | 2021 | Lyophilised Platelet-Rich Fibrin: Physical and Biological Characterisation. | 8 |
| 33760132 | 2021 | HaCaT‑conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF‑AA prevents the dedifferentiation of dermal papilla cells in vitro. | 4 |
Citation
Dessen P
PDGFA (platelet derived growth factor subunit A)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41679/pdgfa
