Identity
HGNC
LOCATION
11p13
LOCUSID
ALIAS
DLDBP,E3BP,OPDX,PDHXD,PDX1,proX
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8050
MIM: 608769
HGNC: 21350
Ensembl: ENSG00000110435
Variants:
dbSNP: 8050
ClinVar: 8050
TCGA: ENSG00000110435
COSMIC: PDHX
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36889194 | 2023 | Cuproptosis-related gene PDHX and heat stress-related HSPD1 as potential key drivers associated with cell stemness, aberrant metabolism and immunosuppression in esophageal carcinoma. | 1 |
| 36889194 | 2023 | Cuproptosis-related gene PDHX and heat stress-related HSPD1 as potential key drivers associated with cell stemness, aberrant metabolism and immunosuppression in esophageal carcinoma. | 1 |
| 33964039 | 2021 | Identification of PDHX as a metabolic target for esophageal squamous cell carcinoma. | 7 |
| 33964039 | 2021 | Identification of PDHX as a metabolic target for esophageal squamous cell carcinoma. | 7 |
| 30012170 | 2018 | Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer. | 37 |
| 30012170 | 2018 | Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer. | 37 |
| 24935220 | 2014 | MicroRNA-26a regulates glucose metabolism by direct targeting PDHX in colorectal cancer cells. | 63 |
| 25087164 | 2014 | Founder p.Arg 446* mutation in the PDHX gene explains over half of cases with congenital lactic acidosis in Roma children. | 7 |
| 24935220 | 2014 | MicroRNA-26a regulates glucose metabolism by direct targeting PDHX in colorectal cancer cells. | 63 |
| 25087164 | 2014 | Founder p.Arg 446* mutation in the PDHX gene explains over half of cases with congenital lactic acidosis in Roma children. | 7 |
| 22766002 | 2012 | Pyruvate dehydrogenase deficiency caused by a new mutation of PDHX gene in two Moroccan patients. | 6 |
| 22766002 | 2012 | Pyruvate dehydrogenase deficiency caused by a new mutation of PDHX gene in two Moroccan patients. | 6 |
| 21194677 | 2011 | Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. | 45 |
| 21194677 | 2011 | Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. | 45 |
| 20800603 | 2010 | Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. | 14 |
Citation
Dessen P
PDHX (pyruvate dehydrogenase complex component X)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43932/pdhx
