Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5164
MIM: 602525
HGNC: 8810
Ensembl: ENSG00000005882
Variants:
dbSNP: 5164
ClinVar: 5164
TCGA: ENSG00000005882
COSMIC: PDK2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33783904 | 2021 | Circular RNA hsa_circ_0005397 promotes hepatocellular carcinoma progression by regulating the miR-326/PDK2 axis. | 9 |
| 34464482 | 2021 | PDK2 leads to cisplatin resistance through suppression of mitochondrial function in ovarian clear cell carcinoma. | 14 |
| 33783904 | 2021 | Circular RNA hsa_circ_0005397 promotes hepatocellular carcinoma progression by regulating the miR-326/PDK2 axis. | 9 |
| 34464482 | 2021 | PDK2 leads to cisplatin resistance through suppression of mitochondrial function in ovarian clear cell carcinoma. | 14 |
| 30578412 | 2020 | Overexpression of PDK2 and PDK3 reflects poor prognosis in acute myeloid leukemia. | 22 |
| 33236596 | 2020 | [Expression Level of Protein Kinase D in Oral Squamous Cell Carcinoma with Diverse Differentiation]. | 1 |
| 30578412 | 2020 | Overexpression of PDK2 and PDK3 reflects poor prognosis in acute myeloid leukemia. | 22 |
| 33236596 | 2020 | [Expression Level of Protein Kinase D in Oral Squamous Cell Carcinoma with Diverse Differentiation]. | 1 |
| 30457021 | 2019 | PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3. | 11 |
| 30457021 | 2019 | PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3. | 11 |
| 29725130 | 2018 | MiR-422a regulates cellular metabolism and malignancy by targeting pyruvate dehydrogenase kinase 2 in gastric cancer. | 36 |
| 29725130 | 2018 | MiR-422a regulates cellular metabolism and malignancy by targeting pyruvate dehydrogenase kinase 2 in gastric cancer. | 36 |
| 28178523 | 2017 | The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism. | 36 |
| 28178523 | 2017 | The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism. | 36 |
| 26607904 | 2016 | Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer. | 41 |
Citation
Dessen P
PDK2 (pyruvate dehydrogenase kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41683/pdk2
