Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5166
MIM: 602527
HGNC: 8812
Ensembl: ENSG00000004799
Variants:
dbSNP: 5166
ClinVar: 5166
TCGA: ENSG00000004799
COSMIC: PDK4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000004799 | ENST00000005178 | Q16654 |
| ENSG00000004799 | ENST00000005178 | A4D1H4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37624974 | 2024 | Inhibition of Pyruvate Dehydrogenase Kinase 4 Attenuates Myocardial and Mitochondrial Injury in Sepsis-Induced Cardiomyopathy. | 0 |
| 38096914 | 2024 | Expression and Role of PDK4 on Childhood Dyslipidemia and Lipid Metabolism in Hyperlipidemic Mice. | 0 |
| 38554157 | 2024 | circFTO from M2 macrophage-derived small extracellular vesicles (sEV) enhances NSCLC malignancy by regulation miR-148a-3pPDK4 axis. | 0 |
| 37624974 | 2024 | Inhibition of Pyruvate Dehydrogenase Kinase 4 Attenuates Myocardial and Mitochondrial Injury in Sepsis-Induced Cardiomyopathy. | 0 |
| 38096914 | 2024 | Expression and Role of PDK4 on Childhood Dyslipidemia and Lipid Metabolism in Hyperlipidemic Mice. | 0 |
| 38554157 | 2024 | circFTO from M2 macrophage-derived small extracellular vesicles (sEV) enhances NSCLC malignancy by regulation miR-148a-3pPDK4 axis. | 0 |
| 36154586 | 2023 | WTAP Mediated the N6-methyladenosine Modification of PDK4 to Regulate the Malignant Behaviors of Colorectal Cancer Cells In Vitro and In Vivo. | 0 |
| 36635027 | 2023 | The Link between Mitochondrial Dysfunction and Sarcopenia: An Update Focusing on the Role of Pyruvate Dehydrogenase Kinase 4. | 6 |
| 37098796 | 2023 | Promotive role of eukaryotic translation initiation factor 4A isoform 3 in ovarian cancer cell growth and aerobic glycolysis through the pyruvate dehydrogenase kinase 4 signaling. | 1 |
| 37224504 | 2023 | Glucocorticoid Receptors Drive Breast Cancer Cell Migration and Metabolic Reprogramming via PDK4. | 5 |
| 37385224 | 2023 | Identification of PDK4 as Hub Gene for Diabetic Nephropathy Using Co-Expression Network Analysis. | 1 |
| 37737961 | 2023 | PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF-1α protein stability and gene expression. | 0 |
| 37863991 | 2023 | High glucose promotes benign prostatic hyperplasia by downregulating PDK4 expression. | 1 |
| 36154586 | 2023 | WTAP Mediated the N6-methyladenosine Modification of PDK4 to Regulate the Malignant Behaviors of Colorectal Cancer Cells In Vitro and In Vivo. | 0 |
| 36635027 | 2023 | The Link between Mitochondrial Dysfunction and Sarcopenia: An Update Focusing on the Role of Pyruvate Dehydrogenase Kinase 4. | 6 |
Citation
Dessen P
PDK4 (pyruvate dehydrogenase kinase 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41684/pdk4
