PECR (peroxisomal trans-2-enoyl-CoA reductase)

2014-11-01  

Identity

HGNC
LOCATION
2q35
LOCUSID
ALIAS
DCRRP,HPDHASE,HSA250303,PVIARL,SDR29C1,TERP

Other Information

Locus ID:

NCBI: 55825
MIM: 605843
HGNC: 18281
Ensembl: ENSG00000115425

Variants:

dbSNP: 55825
ClinVar: 55825
TCGA: ENSG00000115425
COSMIC: PECR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115425ENST00000265322Q9BY49
ENSG00000115425ENST00000442122B4DJS2

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Biosynthesis of unsaturated fatty acidsKEGGko01040
Biosynthesis of unsaturated fatty acidsKEGGhsa01040
PeroxisomeKEGGko04146
PeroxisomeKEGGhsa04146
Fatty acid metabolismKEGGhsa01212
Fatty acid metabolismKEGGko01212
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Peroxisomal lipid metabolismREACTOMER-HSA-390918

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
204631772010Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.15
165461812006Peroxisomal trans-2-enoyl-CoA reductase is involved in phytol degradation.5
227451302012Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal β-oxidation of unsaturated fatty acids.3

Citation

Dessen P

PECR (peroxisomal trans-2-enoyl-CoA reductase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71823/pecr