Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57161
MIM: 614798
HGNC: 8828
Ensembl: ENSG00000139946
Variants:
dbSNP: 57161
ClinVar: 57161
TCGA: ENSG00000139946
COSMIC: PELI2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000139946 | ENST00000267460 | Q9HAT8 |
| ENSG00000139946 | ENST00000559044 | H0YK56 |
| ENSG00000139946 | ENST00000561019 | H0YNF4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38058209 | 2024 | PELI2 regulates early B-cell progenitor differentiation and related leukemia via the IL-7R expression. | 0 |
| 38058209 | 2024 | PELI2 regulates early B-cell progenitor differentiation and related leukemia via the IL-7R expression. | 0 |
| 36776133 | 2023 | A Pellino-2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium-digital keloid dysplasia. | 2 |
| 36776133 | 2023 | A Pellino-2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium-digital keloid dysplasia. | 2 |
| 34387857 | 2021 | K(+) regulates relocation of Pellino-2 to the site of NLRP3 inflammasome activation in macrophages. | 4 |
| 34674267 | 2021 | Pellino-2 in nonimmune cells: novel interaction partners and intracellular localization. | 2 |
| 34387857 | 2021 | K(+) regulates relocation of Pellino-2 to the site of NLRP3 inflammasome activation in macrophages. | 4 |
| 34674267 | 2021 | Pellino-2 in nonimmune cells: novel interaction partners and intracellular localization. | 2 |
| 25027698 | 2014 | The pellino e3 ubiquitin ligases recognize specific phosphothreonine motifs and have distinct substrate specificities. | 9 |
| 25027698 | 2014 | The pellino e3 ubiquitin ligases recognize specific phosphothreonine motifs and have distinct substrate specificities. | 9 |
| 22669975 | 2012 | Pellino 2 is critical for Toll-like receptor/interleukin-1 receptor (TLR/IL-1R)-mediated post-transcriptional control. | 24 |
| 22669975 | 2012 | Pellino 2 is critical for Toll-like receptor/interleukin-1 receptor (TLR/IL-1R)-mediated post-transcriptional control. | 24 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 12804775 | 2003 | Pellino2 activates the mitogen activated protein kinase pathway. | 19 |
Citation
Dessen P
PELI2 (pellino E3 ubiquitin protein ligase family member 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46093/peli2
