PEPD (peptidase D)

2007-07-01  

Identity

HGNC
PEPD
LOCATION
19q13.11
LOCUSID
5184
ALIAS
PROLIDASE
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5184
MIM: 613230
HGNC: 8840
Ensembl: ENSG00000124299

Variants:

dbSNP: 5184
ClinVar: 5184
TCGA: ENSG00000124299
COSMIC: PEPD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124299ENST00000244137P12955
ENSG00000124299ENST00000244137A0A140VJR2
ENSG00000124299ENST00000397032P12955
ENSG00000124299ENST00000436370P12955
ENSG00000124299ENST00000588328K7ES25
ENSG00000124299ENST00000590408V9GYL0
ENSG00000124299ENST00000590755V9GYE4
ENSG00000124299ENST00000651646A0A494C194
ENSG00000124299ENST00000651901A0A494C165

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
194014142009Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.106
170960922007Increased oxidative stress and its relation with collagen metabolism in knee osteoarthritis.38
261597192015Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression.35
179994102008Extracellular matrix and HIF-1 signaling: the role of prolidase.24
189897772009Diagnostic value of serum prolidase enzyme activity to predict the liver histological lesions in non-alcoholic fatty liver disease: a surrogate marker to distinguish steatohepatitis from simple steatosis.19
169999492007Serum prolidase activity and oxidative status in Helicobacter pylori infection.15
186071692008The association of serum prolidase activity with the presence and severity of coronary artery disease.15
198230622009Serum prolidase activity and oxidative status in patients with stage I endometrial cancer.13
222588522012Serum prolidase activity, oxidative stress, and nitric oxide levels in patients with bladder cancer.13
176040132007Serum prolidase activity in patients with hypertension and its relation with left ventricular hypertrophy.12

Citation

Dessen P

PEPD (peptidase D)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47595/pepd