PER3 (period circadian regulator 3)

2003-05-01  

Identity

HGNC
PER3
LOCATION
1p36.23
LOCUSID
8863
ALIAS
FASPS3,GIG13
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8863
MIM: 603427
HGNC: 8847
Ensembl: ENSG00000049246

Variants:

dbSNP: 8863
ClinVar: 8863
TCGA: ENSG00000049246
COSMIC: PER3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000049246ENST00000361923P56645
ENSG00000049246ENST00000361923A2I2N5
ENSG00000049246ENST00000377532P56645
ENSG00000049246ENST00000377541Q8TAR6
ENSG00000049246ENST00000613533P56645
ENSG00000049246ENST00000614998A0A087WV69

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Circadian rhythmKEGGko04710
Circadian rhythmKEGGhsa04710
Herpes simplex infectionKEGGko05168
Herpes simplex infectionKEGGhsa05168
Circadian entrainmentKEGGhsa04713
Circadian entrainmentKEGGko04713

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
173469652007PER3 polymorphism predicts sleep structure and waking performance.152
173469652007PER3 polymorphism predicts sleep structure and waking performance.152
157905882005Deregulated expression of the PER1, PER2 and PER3 genes in breast cancers.119
200721162010Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder.91
165287482006Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder.88
165287482006Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder.88
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
126553192003Circadian clock-related polymorphisms in seasonal affective disorder and their relevance to diurnal preference.74
226894352012Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors.60
197167322010PERIOD3, circadian phenotypes, and sleep homeostasis.56

Citation

Dessen P

PER3 (period circadian regulator 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41691/per3