PES1 (pescadillo ribosomal biogenesis factor 1)

2003-02-01  

Identity

HGNC
LOCATION
22q12.2
LOCUSID
ALIAS
NOP7,PES
FUSION GENES

Other Information

Locus ID:

NCBI: 23481
MIM: 605819
HGNC: 8848
Ensembl: ENSG00000100029

Variants:

dbSNP: 23481
ClinVar: 23481
TCGA: ENSG00000100029
COSMIC: PES1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100029ENST00000335214O00541
ENSG00000100029ENST00000354694O00541
ENSG00000100029ENST00000354694B2RDF2
ENSG00000100029ENST00000402281B3KXD6
ENSG00000100029ENST00000402284B5MCF9
ENSG00000100029ENST00000405677B3KXD6
ENSG00000100029ENST00000406208H7BYY8
ENSG00000100029ENST00000441668H7C267

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
362177582023Pescadillo ribosomal biogenesis factor 1 reduction suppresses tumour growth and renders chemosensitivity of head and neck squamous cell carcinoma.2
367750582023Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy.1
370769852023PES1 is a biomarker of head and neck squamous cell carcinoma and is associated with the tumor microenvironment.1
362177582023Pescadillo ribosomal biogenesis factor 1 reduction suppresses tumour growth and renders chemosensitivity of head and neck squamous cell carcinoma.2
367750582023Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy.1
370769852023PES1 is a biomarker of head and neck squamous cell carcinoma and is associated with the tumor microenvironment.1
324483712020microRNA-1271 impedes the development of prostate cancer by downregulating PES1 and upregulating ERβ.6
324483712020microRNA-1271 impedes the development of prostate cancer by downregulating PES1 and upregulating ERβ.6
306300062019PES1 enhances proliferation and tumorigenesis in hepatocellular carcinoma via the PI3K/AKT pathway.17
307053672019PES1 promotes the occurrence and development of papillary thyroid cancer by upregulating the ERα/ERβ protein ratio.10
311062662019PES1 is a critical component of telomerase assembly and regulates cellular senescence.26
311278522019PES1 is regulated by CD44 in liver cancer stem cells via miR-105-5p.8
317187042019PES1 promotes BET inhibitors resistance and cells proliferation through increasing c-Myc expression in pancreatic cancer.21
306300062019PES1 enhances proliferation and tumorigenesis in hepatocellular carcinoma via the PI3K/AKT pathway.17
307053672019PES1 promotes the occurrence and development of papillary thyroid cancer by upregulating the ERα/ERβ protein ratio.10

Citation

Dessen P

PES1 (pescadillo ribosomal biogenesis factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41692/pes1