PFDN6 (prefoldin subunit 6)

2007-07-01  

Identity

HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
H2-KE2,HKE2,KE-2,PFD6
FUSION GENES

Other Information

Locus ID:

NCBI: 10471
MIM: 605660
HGNC: 4926
Ensembl: ENSG00000204220

Variants:

dbSNP: 10471
ClinVar: 10471
TCGA: ENSG00000204220
COSMIC: PFDN6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204220ENST00000374606O15212
ENSG00000204220ENST00000374606Q5STK2
ENSG00000204220ENST00000374607O15212
ENSG00000204220ENST00000374607Q5STK2
ENSG00000204220ENST00000374610O15212
ENSG00000204220ENST00000374610Q5STK2
ENSG00000204220ENST00000395131O15212
ENSG00000204220ENST00000395131Q5STK2
ENSG00000204220ENST00000463584A2AB88

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Protein foldingREACTOMER-HSA-391251
Chaperonin-mediated protein foldingREACTOMER-HSA-390466
Cooperation of Prefoldin and TriC/CCT in actin and tubulin foldingREACTOMER-HSA-389958
Prefoldin mediated transfer of substrate to CCT/TriCREACTOMER-HSA-389957

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.51
194506872009High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes.42
172573222007Characterization of HKE2: an ancient antigen encoded in the major histocompatibility complex.4

Citation

Dessen P

PFDN6 (prefoldin subunit 6)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47656/pfdn6