PGC (progastricsin)

2007-02-01  

Identity

HGNC
LOCATION
6p21.1
LOCUSID
ALIAS
PEPC,PGII
FUSION GENES

Other Information

Locus ID:

NCBI: 5225
MIM: 169740
HGNC: 8890
Ensembl: ENSG00000096088

Variants:

dbSNP: 5225
ClinVar: 5225
TCGA: ENSG00000096088
COSMIC: PGC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000096088ENST00000356667Q4VXA6
ENSG00000096088ENST00000373025P20142
ENSG00000096088ENST00000415707A2A3L9
ENSG00000096088ENST00000425343P20142

Expression (GTEx)

0
5000
10000
15000
20000
25000
30000
35000
40000

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
240091392014Cancer development based on chronic active gastritis and resulting gastric atrophy as assessed by serum levels of pepsinogen and Helicobacter pylori antibody titer.46
127593532003Processing of seminal plasma hCAP-18 to ALL-38 by gastricsin: a novel mechanism of generating antimicrobial peptides in vagina.45
126981902003Pepsinogen A, pepsinogen C, and gastrin as markers of atrophic chronic gastritis in European dyspeptics.32
234553812013Helicobacter pylori-related host gene polymorphisms associated with susceptibility of gastric carcinogenesis: a two-stage case-control study in Chinese.23
156883782005Histologic and serum risk markers for noncardia early gastric cancer.20
213034082011Serum pepsinogen II: a neglected but useful biomarker to differentiate between diseased and normal stomachs.20
182560272008Pepsinogen C proteolytic processing of surfactant protein B.18
188442222009Serum pepsinogens and risk of esophageal squamous dysplasia.18
197310262009The validity of a biomarker method for indirect detection of gastric mucosal atrophy versus standard histopathology.17

Citation

Dessen P

PGC (progastricsin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43776/pgc