PGGT1B (protein geranylgeranyltransferase type I subunit beta)

2007-02-01  

Identity

HGNC
LOCATION
5q22.3
LOCUSID
ALIAS
BGGI,GGTI
FUSION GENES

Other Information

Locus ID:

NCBI: 5229
MIM: 602031
HGNC: 8895
Ensembl: ENSG00000164219

Variants:

dbSNP: 5229
ClinVar: 5229
TCGA: ENSG00000164219
COSMIC: PGGT1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164219ENST00000379615P53609
ENSG00000164219ENST00000419445P53609

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
154516702004Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.87
204039972010Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer.30
196672182009Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis.21
221603082012Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle.17
145988912003Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor.15
204469222010Inhibition of GGTase-I and FTase disrupts cytoskeletal organization of human PC-3 prostate cancer cells.6
234753912013Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion.2

Citation

Dessen P

PGGT1B (protein geranylgeranyltransferase type I subunit beta)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43928/pggt1b