PHF10 (PHD finger protein 10)

2010-10-01  

Identity

HGNC
PHF10
LOCATION
6q27
LOCUSID
55274
ALIAS
BAF45A,XAP135

Other Information

Locus ID:

NCBI: 55274
MIM: 613069
HGNC: 18250
Ensembl: ENSG00000130024

Variants:

dbSNP: 55274
ClinVar: 55274
TCGA: ENSG00000130024
COSMIC: PHF10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130024ENST00000339209Q8WUB8
ENSG00000130024ENST00000366780Q8WUB8
ENSG00000130024ENST00000612128S5FZ81
ENSG00000130024ENST00000621772Q8WUB8
ENSG00000130024ENST00000621772S5FMB0

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
200682942009PHF10 is required for cell proliferation in normal and SV40-immortalized human fibroblast cells.5
205307142010A novel plant homeodomain finger 10-mediated antiapoptotic mechanism involving repression of caspase-3 in gastric cancer cells.5
247633042014Mammalian cells contain two functionally distinct PBAF complexes incorporating different isoforms of PHF10 signature subunit.4
287171952017Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP.3
272398532016[PHF10 isoforms are phosphorylated in the PBAF mammalian chromatin remodeling complex].2
310120172019Oncogene c-MYC Controls the Expression of PHF10 Subunit of PBAF Chromatin Remodeling Complex in SW620 Cell Line.2
271937242016The level of the Phf10 protein, a PBAF chromatin-remodeling complex subunit, correlates with the Mts1/S100A4 expression in human cancer cell lines.0

Citation

Dessen P

PHF10 (PHD finger protein 10)

Atlas Genet Cytogenet Oncol Haematol. 2010-10-01

Online version: http://atlasgeneticsoncology.org/gene/51693/phf10