Identity
HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
CGI-202,HEL-S-132P,HSPC141,PHP,PHP14
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29085
MIM: 610167
HGNC: 30033
Ensembl: ENSG00000054148
Variants:
dbSNP: 29085
ClinVar: 29085
TCGA: ENSG00000054148
COSMIC: PHPT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000054148 | ENST00000247665 | Q9NRX4 |
| ENSG00000054148 | ENST00000247665 | V9HWC4 |
| ENSG00000054148 | ENST00000371661 | Q9NRX4 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38747379 | 2024 | A salt bridge of the C-terminal carboxyl group regulates PHPT1 substrate affinity and catalytic activity. | 0 |
| 38747379 | 2024 | A salt bridge of the C-terminal carboxyl group regulates PHPT1 substrate affinity and catalytic activity. | 0 |
| 35411430 | 2022 | FBXO32 targets PHPT1 for ubiquitination to regulate the growth of EGFR mutant lung cancer. | 9 |
| 35411430 | 2022 | FBXO32 targets PHPT1 for ubiquitination to regulate the growth of EGFR mutant lung cancer. | 9 |
| 29098317 | 2018 | PHP14 regulates hepatic stellate cells migration in liver fibrosis via mediating TGF-β1 signaling to PI3Kγ/AKT/Rac1 pathway. | 9 |
| 29630837 | 2018 | Facile, Fluorogenic Assay for Protein Histidine Phosphatase Activity. | 6 |
| 29787434 | 2018 | Influence of Confounding Factors on Radiation Dose Estimation Using In Vivo Validated Transcriptional Biomarkers. | 10 |
| 29098317 | 2018 | PHP14 regulates hepatic stellate cells migration in liver fibrosis via mediating TGF-β1 signaling to PI3Kγ/AKT/Rac1 pathway. | 9 |
| 29630837 | 2018 | Facile, Fluorogenic Assay for Protein Histidine Phosphatase Activity. | 6 |
| 29787434 | 2018 | Influence of Confounding Factors on Radiation Dose Estimation Using In Vivo Validated Transcriptional Biomarkers. | 10 |
| 27034094 | 2016 | Structural and activity characterization of human PHPT1 after oxidative modification. | 10 |
| 27034094 | 2016 | Structural and activity characterization of human PHPT1 after oxidative modification. | 10 |
| 25574816 | 2015 | Phosphohistidine phosphatase 1 (PHPT1) also dephosphorylates phospholysine of chemically phosphorylated histone H1 and polylysine. | 12 |
| 26537769 | 2015 | Nuclear expression and clinical significance of phosphohistidine phosphatase 1 in clear-cell renal cell carcinoma. | 10 |
| 25574816 | 2015 | Phosphohistidine phosphatase 1 (PHPT1) also dephosphorylates phospholysine of chemically phosphorylated histone H1 and polylysine. | 12 |
Citation
Dessen P
PHPT1 (phosphohistidine phosphatase 1)
Atlas Genet Cytogenet Oncol Haematol. 2010-03-01
Online version: http://atlasgeneticsoncology.org/gene/51359/phpt1
