PIBF1 (progesterone immunomodulatory binding factor 1)

2007-02-01  

Identity

HGNC
PIBF1
LOCATION
13q21.33
LOCUSID
10464
ALIAS
C13orf24,CEP90,JBTS33,PIBF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10464
MIM: 607532
HGNC: 23352
Ensembl: ENSG00000083535

Variants:

dbSNP: 10464
ClinVar: 10464
TCGA: ENSG00000083535
COSMIC: PIBF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000083535ENST00000326291Q8WXW3
ENSG00000083535ENST00000615625Q8WXW3
ENSG00000083535ENST00000617689A0A087WUI6

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
198984812009Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.131
212243922011The pericentriolar satellite protein CEP90 is crucial for integrity of the mitotic spindle pole.30
203676222010PIBF: the double edged sword. Pregnancy and tumor.26
193719562009Progesterone-induced blocking factor (PIBF) modulates cytokine production by lymphocytes from women with recurrent miscarriage or preterm delivery.19
279185642017Interleukin-33-induced expression of PIBF1 by decidual B cells protects against preterm labor.17
231102112012CEP90 is required for the assembly and centrosomal accumulation of centriolar satellites, which is essential for primary cilia formation.14
153053752004PIBF (progesterone induced blocking factor) is overexpressed in highly proliferating cells and associated with the centrosome.13
152690992004Urinary progesterone-induced blocking factor concentration is related to pregnancy outcome.12
238072092013Progesterone-induced blocking factor differentially regulates trophoblast and tumor invasion by altering matrix metalloproteinase activity.10
146341072003Molecular cloning and immunologic characterization of a novel cDNA coding for progesterone-induced blocking factor.9

Citation

Dessen P

PIBF1 (progesterone immunomodulatory binding factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43918/pibf1