PIP4P1 (phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1)

2017-09-01 Affiliation

HGNC

PIP4P1

LOCATION

14q11.2

LOCUSID

90809

ALIAS

C14orf9,TMEM55B

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

dbSNP: 90809
ClinVar: 90809
TCGA: ENSG00000165782
COSMIC: PIP4P1

Pathway	Source	External ID
Phosphatidylinositol signaling system	KEGG	ko04070
Phosphatidylinositol signaling system	KEGG	hsa04070
Gene Expression	REACTOME	R-HSA-74160
Generic Transcription Pathway	REACTOME	R-HSA-212436
Transcriptional Regulation by TP53	REACTOME	R-HSA-3700989
Metabolism	REACTOME	R-HSA-1430728
Metabolism of lipids and lipoproteins	REACTOME	R-HSA-556833
Phospholipid metabolism	REACTOME	R-HSA-1483257
PI Metabolism	REACTOME	R-HSA-1483255
Regulation of TP53 Activity	REACTOME	R-HSA-5633007
Regulation of TP53 Activity through Acetylation	REACTOME	R-HSA-6804758
PI5P Regulates TP53 Acetylation	REACTOME	R-HSA-6811555
Synthesis of PIPs in the nucleus	REACTOME	R-HSA-8847453

Not detected

Low

Medium

High

Pubmed ID	Year	Title	Citations
16365287	2005	The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases.	31
17940011	2007	Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis.	27
29146937	2017	TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes.	17
25035345	2014	Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism.	7
29644770	2018	TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation.	2

Dessen P

PIP4P1 (phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-09-01