Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8544
MIM: 300931
HGNC: 30048
Ensembl: ENSG00000087842
Variants:
dbSNP: 8544
ClinVar: 8544
TCGA: ENSG00000087842
COSMIC: PIR
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000087842 | ENST00000380420 | O00625 |
| ENSG00000087842 | ENST00000380420 | A0A024RBX6 |
| ENSG00000087842 | ENST00000380421 | O00625 |
| ENSG00000087842 | ENST00000380421 | A0A024RBX6 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33373853 | 2021 | Pirin is a nuclear redox-sensitive modulator of autophagy-dependent ferroptosis. | 22 |
| 33389678 | 2021 | PIWIL1 interacting RNA piR-017061 inhibits pancreatic cancer growth via regulating EFNA5. | 13 |
| 33373853 | 2021 | Pirin is a nuclear redox-sensitive modulator of autophagy-dependent ferroptosis. | 22 |
| 33389678 | 2021 | PIWIL1 interacting RNA piR-017061 inhibits pancreatic cancer growth via regulating EFNA5. | 13 |
| 30444038 | 2019 | Pirin: a potential novel therapeutic target for castration-resistant prostate cancer regulated by miR-455-5p. | 20 |
| 31500513 | 2019 | PIR promotes tumorigenesis of breast cancer by upregulating cell cycle activator E2F1. | 9 |
| 30444038 | 2019 | Pirin: a potential novel therapeutic target for castration-resistant prostate cancer regulated by miR-455-5p. | 20 |
| 31500513 | 2019 | PIR promotes tumorigenesis of breast cancer by upregulating cell cycle activator E2F1. | 9 |
| 28825294 | 2017 | Redox-Specific Allosteric Modulation of the Conformational Dynamics of κB DNA by Pirin in the NF-κB Supramolecular Complex. | 4 |
| 28825294 | 2017 | Redox-Specific Allosteric Modulation of the Conformational Dynamics of κB DNA by Pirin in the NF-κB Supramolecular Complex. | 4 |
| 25680527 | 2015 | Pirin regulates epithelial to mesenchymal transition independently of Bcl3-Slug signaling. | 20 |
| 25680527 | 2015 | Pirin regulates epithelial to mesenchymal transition independently of Bcl3-Slug signaling. | 20 |
| 24272884 | 2014 | Pirin down-regulates the EAF2/U19 protein and alleviates its growth inhibition in prostate cancer cells. | 7 |
| 24390086 | 2014 | Basal PIR expression in HeLa cells is driven by NRF2 via evolutionary conserved antioxidant response element. | 16 |
| 24272884 | 2014 | Pirin down-regulates the EAF2/U19 protein and alleviates its growth inhibition in prostate cancer cells. | 7 |
Citation
Dessen P
PIR (pirin)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41722/pir
