Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23228
MIM: 614276
HGNC: 9064
Ensembl: ENSG00000154822
Variants:
dbSNP: 23228
ClinVar: 23228
TCGA: ENSG00000154822
COSMIC: PLCL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000154822 | ENST00000419842 | H7C276 |
| ENSG00000154822 | ENST00000432376 | Q9UPR0 |
| ENSG00000154822 | ENST00000615277 | Q9UPR0 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA26097 | CASR | Gene | Pathway | associated | |||
| PA33759 | PRKCA | Gene | Pathway | associated | |||
| PA33761 | PRKCB | Gene | Pathway | associated | |||
| PA33766 | PRKCG | Gene | Pathway | associated | |||
| PA33767 | PRKCH | Gene | Pathway | associated | |||
| PA33768 | PRKCI | Gene | Pathway | associated | |||
| PA33771 | PRKD1 | Gene | Pathway | associated | |||
| PA33775 | PRKCZ | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31970634 | 2020 | Two Novel SNPs in the PLCL2 Gene Associated with Large Artery Atherosclerotic Stroke Identified by Fine-Mapping. | 2 |
| 32392189 | 2020 | [Functional Hypermethylation of ALDH1L1, PLCL2, and PPP2R3A in Colon Cancer]. | 3 |
| 31970634 | 2020 | Two Novel SNPs in the PLCL2 Gene Associated with Large Artery Atherosclerotic Stroke Identified by Fine-Mapping. | 2 |
| 32392189 | 2020 | [Functional Hypermethylation of ALDH1L1, PLCL2, and PPP2R3A in Colon Cancer]. | 3 |
| 24916648 | 2015 | A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese. | 25 |
| 25880423 | 2015 | Identification of NF-κB and PLCL2 as new susceptibility genes and highlights on a potential role of IRF8 through interferon signature modulation in systemic sclerosis. | 20 |
| 24916648 | 2015 | A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese. | 25 |
| 25880423 | 2015 | Identification of NF-κB and PLCL2 as new susceptibility genes and highlights on a potential role of IRF8 through interferon signature modulation in systemic sclerosis. | 20 |
| 19898481 | 2009 | Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. | 160 |
| 19898481 | 2009 | Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. | 160 |
Citation
Dessen P
PLCL2 (phospholipase C like 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46958/plcl2
