PLEKHB2 (pleckstrin homology domain containing B2)

2014-08-01  

Identity

HGNC
LOCATION
2q21.1
LOCUSID
ALIAS
EVT2
FUSION GENES

Other Information

Locus ID:

NCBI: 55041
MIM: 618452
HGNC: 19236
Ensembl: ENSG00000115762

Variants:

dbSNP: 55041
ClinVar: 55041
TCGA: ENSG00000115762
COSMIC: PLEKHB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115762ENST00000234115Q96CS7
ENSG00000115762ENST00000403716A0A0A0MSE9
ENSG00000115762ENST00000404460B7WPA5
ENSG00000115762ENST00000409158Q96CS7
ENSG00000115762ENST00000409279Q96CS7
ENSG00000115762ENST00000409279A0A024QZ35
ENSG00000115762ENST00000409612Q96CS7
ENSG00000115762ENST00000409612A0A024QZ35
ENSG00000115762ENST00000438882Q96CS7
ENSG00000115762ENST00000439822A0A0A0MSI4
ENSG00000115762ENST00000628582Q96CS7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
219113782011Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes.53
290934432017Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells.7
222817402012Structural basis of the strict phospholipid binding specificity of the pleckstrin homology domain of human evectin-2.3

Citation

Dessen P

PLEKHB2 (pleckstrin homology domain containing B2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54542/plekhb2