PLIN5 (perilipin 5)

2014-11-01 Affiliation

Identity

HGNC

PLIN5

LOCATION

19p13.3

LOCUSID

440503

ALIAS

LSDA5,LSDP5,MLDP,OXPAT

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 440503
MIM: 613248
HGNC: 33196
Ensembl: ENSG00000214456

Variants:

dbSNP: 440503
ClinVar: 440503
TCGA: ENSG00000214456
COSMIC: PLIN5

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000214456	ENST00000381848	Q00G26
ENSG00000214456	ENST00000586133	K7EIX1
ENSG00000214456	ENST00000592610	K7EIX1

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
PPAR signaling pathway	KEGG	ko03320
PPAR signaling pathway	KEGG	hsa03320

References

Pubmed ID	Year	Title	Citations
21393244	2011	Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein.	95
23129790	2013	Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5.	42
19602560	2009	Adipocyte differentiation-related protein and OXPAT in rat and human skeletal muscle: involvement in lipid accumulation and type 2 diabetes mellitus.	30
22667335	2012	Perilipin family (PLIN) proteins in human skeletal muscle: the effect of sex, obesity, and endurance training.	21
30591149	2018	Super-resolution microscopy localizes perilipin 5 at lipid droplet-mitochondria interaction sites and at lipid droplets juxtaposing to perilipin 2.	6
25054327	2014	Cellular localization and associations of the major lipolytic proteins in human skeletal muscle at rest and during exercise.	5
27428080	2016	Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation.	2
26447519	2016	Higher muscle content of perilipin 5 and endothelial lipase protein in trained than untrained middle-aged men.	1
21632259	2011	Oxidative tissue: perilipin 5 links storage with the furnace.	0
22127648	2012	The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria.	0

Citation

Dessen P

PLIN5 (perilipin 5)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71998/plin5