PLK5 (polo like kinase 5 (inactive))

2011-09-01  

Identity

HGNC
PLK5
LOCATION
19p13.3
LOCUSID
126520
ALIAS
PLK-5,PLK5P,SgK384ps

Other Information

Locus ID:

NCBI: 126520
HGNC: 27001
Ensembl: ENSG00000185988

Variants:

dbSNP: 126520
ClinVar: 126520
TCGA: ENSG00000185988
COSMIC: PLK5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185988ENST00000334770Q496M5
ENSG00000185988ENST00000454744Q496M5
ENSG00000185988ENST00000588430Q496M5
ENSG00000185988ENST00000642079A0A286YFL1

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
212453852011Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression.37
269084402016Genetic mutations associated with metastatic clear cell renal cell carcinoma.3

Citation

Dessen P

PLK5 (polo like kinase 5 (inactive))

Atlas Genet Cytogenet Oncol Haematol. 2011-09-01

Online version: http://atlasgeneticsoncology.org/gene/52363/plk5