PLS3 (plastin 3)

2008-12-01  

Identity

HGNC
LOCATION
Xq23
LOCUSID
ALIAS
BMND18,T-plastin
FUSION GENES

Other Information

Locus ID:

NCBI: 5358
MIM: 300131
HGNC: 9091
Ensembl: ENSG00000102024

Variants:

dbSNP: 5358
ClinVar: 5358
TCGA: ENSG00000102024
COSMIC: PLS3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102024ENST00000289290P13797
ENSG00000102024ENST00000355899P13797
ENSG00000102024ENST00000420625A0A0A0MSQ0
ENSG00000102024ENST00000473026U3KQI3
ENSG00000102024ENST00000481823F2Z2Z9
ENSG00000102024ENST00000489283F2Z2Z9
ENSG00000102024ENST00000497870H7C4N2
ENSG00000102024ENST00000539310P13797
ENSG00000102024ENST00000626746F2Z2Z9

Expression (GTEx)

0
100
200
300
400
500
600
700
800

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373475552024PLS3 promotes papillary thyroid carcinoma progression by activating the Notch signaling pathway.0
380431022024PLS3 Mutations in X-Linked Osteoporosis: Clinical and Genetic Features in Five New Families.1
388351172024T-plastin contributes to epithelial-mesenchymal transition in human lung cancer cells through FAK/AKT/Slug axis signaling pathway.0
373475552024PLS3 promotes papillary thyroid carcinoma progression by activating the Notch signaling pathway.0
380431022024PLS3 Mutations in X-Linked Osteoporosis: Clinical and Genetic Features in Five New Families.1
388351172024T-plastin contributes to epithelial-mesenchymal transition in human lung cancer cells through FAK/AKT/Slug axis signaling pathway.0
366072732023Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy.2
368129142023Epigenetic regulation of plastin 3 expression by the macrosatellite DXZ4 and the transcriptional regulator CHD4.0
377517382023PLS3 missense variants affecting the actin-binding domains cause X-linked congenital diaphragmatic hernia and body-wall defects.0
366072732023Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy.2
368129142023Epigenetic regulation of plastin 3 expression by the macrosatellite DXZ4 and the transcriptional regulator CHD4.0
377517382023PLS3 missense variants affecting the actin-binding domains cause X-linked congenital diaphragmatic hernia and body-wall defects.0
357528172022Identification of a novel splicing mutation and genotype-phenotype correlations in rare PLS3-related childhood-onset osteoporosis.2
357528172022Identification of a novel splicing mutation and genotype-phenotype correlations in rare PLS3-related childhood-onset osteoporosis.2
338028382021Expression and Localization of Thrombospondins, Plastin 3, and STIM1 in Different Cartilage Compartments of the Osteoarthritic Varus Knee.6

Citation

Dessen P

PLS3 (plastin 3)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50542/pls3