Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5366
MIM: 604959
HGNC: 9108
Ensembl: ENSG00000141682
Variants:
dbSNP: 5366
ClinVar: 5366
TCGA: ENSG00000141682
COSMIC: PMAIP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000141682 | ENST00000269518 | Q13794 |
| ENSG00000141682 | ENST00000269518 | A0A0S2Z4V2 |
| ENSG00000141682 | ENST00000316660 | Q13794 |
| ENSG00000141682 | ENST00000316660 | A0A0S2Z490 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38503887 | 2024 | Noxa inhibits oncogenesis through ZNF519 in gastric cancer and is suppressed by hsa-miR-200b-3p. | 1 |
| 38692009 | 2024 | The mechanism of mitochondrial metabolic gene PMAIP1 involved in Alzheimer's disease process based on bioinformatics analysis and experimental validation. | 0 |
| 38503887 | 2024 | Noxa inhibits oncogenesis through ZNF519 in gastric cancer and is suppressed by hsa-miR-200b-3p. | 1 |
| 38692009 | 2024 | The mechanism of mitochondrial metabolic gene PMAIP1 involved in Alzheimer's disease process based on bioinformatics analysis and experimental validation. | 0 |
| 37741850 | 2023 | NOXA expression is downregulated in human breast cancer undergoing incomplete pathological response and senescence after neoadjuvant chemotherapy. | 2 |
| 37741850 | 2023 | NOXA expression is downregulated in human breast cancer undergoing incomplete pathological response and senescence after neoadjuvant chemotherapy. | 2 |
| 32648994 | 2021 | NOXA upregulation by the prohibitin-binding compound fluorizoline is transcriptionally regulated by integrated stress response-induced ATF3 and ATF4. | 14 |
| 32682341 | 2021 | Noxa upregulation and 5-gene apoptotic biomarker panel in colorectal cancer. | 3 |
| 33420360 | 2021 | TAS4464, a NEDD8-activating enzyme inhibitor, activates both intrinsic and extrinsic apoptotic pathways via c-Myc-mediated regulation in acute myeloid leukemia. | 15 |
| 33712558 | 2021 | Cullin-5 neddylation-mediated NOXA degradation is enhanced by PRDX1 oligomers in colorectal cancer. | 12 |
| 34903710 | 2021 | The BH3-only protein NOXA serves as an independent predictor of breast cancer patient survival and defines susceptibility to microtubule targeting agents. | 6 |
| 32648994 | 2021 | NOXA upregulation by the prohibitin-binding compound fluorizoline is transcriptionally regulated by integrated stress response-induced ATF3 and ATF4. | 14 |
| 32682341 | 2021 | Noxa upregulation and 5-gene apoptotic biomarker panel in colorectal cancer. | 3 |
| 33420360 | 2021 | TAS4464, a NEDD8-activating enzyme inhibitor, activates both intrinsic and extrinsic apoptotic pathways via c-Myc-mediated regulation in acute myeloid leukemia. | 15 |
| 33712558 | 2021 | Cullin-5 neddylation-mediated NOXA degradation is enhanced by PRDX1 oligomers in colorectal cancer. | 12 |
Citation
Dessen P
PMAIP1 (phorbol-12-myristate-13-acetate-induced protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41754/pmaip1
