Identity
HGNC
LOCATION
10q25.3
LOCUSID
ALIAS
PL,PNLIPD,PTL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5406
MIM: 246600
HGNC: 9155
Ensembl: ENSG00000175535
Variants:
dbSNP: 5406
ClinVar: 5406
TCGA: ENSG00000175535
COSMIC: PNLIP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000175535 | ENST00000369221 | P16233 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38081381 | 2024 | Pancreatic lipase and its related proteins: where are we now? | 0 |
| 38081381 | 2024 | Pancreatic lipase and its related proteins: where are we now? | 0 |
| 36583522 | 2023 | In vitro anti-obesity activity by pancreatic lipase inhibition - Simple HPLC approach using EVOO as natural substrate. | 0 |
| 37270400 | 2023 | Identification of protease-sensitive but not misfolding PNLIP variants in familial and hereditary pancreatitis. | 3 |
| 36583522 | 2023 | In vitro anti-obesity activity by pancreatic lipase inhibition - Simple HPLC approach using EVOO as natural substrate. | 0 |
| 37270400 | 2023 | Identification of protease-sensitive but not misfolding PNLIP variants in familial and hereditary pancreatitis. | 3 |
| 34373204 | 2021 | Missense PNLIP mutations impeding pancreatic lipase secretion cause protein misfolding and endoplasmic reticulum stress. | 6 |
| 34373204 | 2021 | Missense PNLIP mutations impeding pancreatic lipase secretion cause protein misfolding and endoplasmic reticulum stress. | 6 |
| 31917686 | 2020 | Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation. | 60 |
| 31917686 | 2020 | Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation. | 60 |
| 30789418 | 2019 | Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis. | 20 |
| 30789418 | 2019 | Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis. | 20 |
| 27243230 | 2016 | Clinical efficacy of serum lipase subtype analysis for the differential diagnosis of pancreatic and non-pancreatic lipase elevation. | 1 |
| 27243230 | 2016 | Clinical efficacy of serum lipase subtype analysis for the differential diagnosis of pancreatic and non-pancreatic lipase elevation. | 1 |
| 25862608 | 2015 | A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding. | 18 |
Citation
Dessen P
PNLIP (pancreatic lipase)
Atlas Genet Cytogenet Oncol Haematol. 2012-11-01
Online version: http://atlasgeneticsoncology.org/gene/52946/pnlip
