Identity
HGNC
LOCATION
20q11.21
LOCUSID
ALIAS
DDD2,FUT12,O-FUT,O-Fuc-T,O-FucT-1,OFUCT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23509
MIM: 607491
HGNC: 14988
Ensembl: ENSG00000101346
Variants:
dbSNP: 23509
ClinVar: 23509
TCGA: ENSG00000101346
COSMIC: POFUT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101346 | ENST00000375730 | Q9H488 |
| ENSG00000101346 | ENST00000375749 | Q9H488 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38500386 | 2024 | POFUT1 and PLAGL2 are characteristic markers of mucinous colorectal cancer associated with MUC2 expression. | 0 |
| 38976017 | 2024 | Analysis of endogenous NOTCH1 from POFUT1 S162L patient fibroblasts reveals the importance of the O-fucose modification on EGF12 in human development. | 0 |
| 38500386 | 2024 | POFUT1 and PLAGL2 are characteristic markers of mucinous colorectal cancer associated with MUC2 expression. | 0 |
| 38976017 | 2024 | Analysis of endogenous NOTCH1 from POFUT1 S162L patient fibroblasts reveals the importance of the O-fucose modification on EGF12 in human development. | 0 |
| 36624091 | 2023 | Circular RNA circPOFUT1 enhances malignant phenotypes and autophagy-associated chemoresistance via sequestrating miR-488-3p to activate the PLAG1-ATG12 axis in gastric cancer. | 3 |
| 37432515 | 2023 | Preliminary study on the mechanism of POFUT1 in colorectal cancer. | 0 |
| 37641160 | 2023 | Overexpression of POFUT1 promotes malignant phenotype and mediates perineural invasion in head and neck squamous cell carcinoma. | 1 |
| 36624091 | 2023 | Circular RNA circPOFUT1 enhances malignant phenotypes and autophagy-associated chemoresistance via sequestrating miR-488-3p to activate the PLAG1-ATG12 axis in gastric cancer. | 3 |
| 37432515 | 2023 | Preliminary study on the mechanism of POFUT1 in colorectal cancer. | 0 |
| 37641160 | 2023 | Overexpression of POFUT1 promotes malignant phenotype and mediates perineural invasion in head and neck squamous cell carcinoma. | 1 |
| 34251584 | 2021 | POFUT1 acts as a tumor promoter in glioblastoma by enhancing the activation of Notch signaling. | 7 |
| 34251584 | 2021 | POFUT1 acts as a tumor promoter in glioblastoma by enhancing the activation of Notch signaling. | 7 |
| 31411736 | 2020 | Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression. | 24 |
| 31411736 | 2020 | Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression. | 24 |
| 31201143 | 2019 | poFUT1 promotes endometrial decidualization by enhancing the O-fucosylation of Notch1. | 10 |
Citation
Dessen P
POFUT1 (protein O-fucosyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47518/pofut1
