Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5423
MIM: 174760
HGNC: 9174
Ensembl: ENSG00000070501
Variants:
dbSNP: 5423
ClinVar: 5423
TCGA: ENSG00000070501
COSMIC: POLB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37806619 | 2024 | Coordination between human DNA polymerase β and apurinic/apyrimidinic endonuclease 1 in the course of DNA repair. | 1 |
| 38135179 | 2024 | Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in the Base Excision Repair Pathway. | 1 |
| 38245510 | 2024 | DNA polymerase beta connects tumorigenicity with the circadian clock in liver cancer through the epigenetic demethylation of Per1. | 0 |
| 38673769 | 2024 | The Impact of SNP-Induced Amino Acid Substitutions L19P and G66R in the dRP-Lyase Domain of Human DNA Polymerase β on Enzyme Activities. | 0 |
| 37806619 | 2024 | Coordination between human DNA polymerase β and apurinic/apyrimidinic endonuclease 1 in the course of DNA repair. | 1 |
| 38135179 | 2024 | Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in the Base Excision Repair Pathway. | 1 |
| 38245510 | 2024 | DNA polymerase beta connects tumorigenicity with the circadian clock in liver cancer through the epigenetic demethylation of Per1. | 0 |
| 38673769 | 2024 | The Impact of SNP-Induced Amino Acid Substitutions L19P and G66R in the dRP-Lyase Domain of Human DNA Polymerase β on Enzyme Activities. | 0 |
| 36689867 | 2023 | Fluorescently labeled human apurinic/apyrimidinic endonuclease APE1 reveals effects of DNA polymerase β on the APE1-DNA interaction. | 2 |
| 36982964 | 2023 | Human Polβ Natural Polymorphic Variants G118V and R149I Affects Substate Binding and Catalysis. | 4 |
| 37095208 | 2023 | Targeting DNA polymerase β elicits synthetic lethality with mismatch repair deficiency in acute lymphoblastic leukemia. | 1 |
| 37174699 | 2023 | The Activity of Natural Polymorphic Variants of Human DNA Polymerase β Having an Amino Acid Substitution in the Transferase Domain. | 2 |
| 37298543 | 2023 | The Impact of Human DNA Glycosylases on the Activity of DNA Polymerase β toward Various Base Excision Repair Intermediates. | 3 |
| 36689867 | 2023 | Fluorescently labeled human apurinic/apyrimidinic endonuclease APE1 reveals effects of DNA polymerase β on the APE1-DNA interaction. | 2 |
| 36982964 | 2023 | Human Polβ Natural Polymorphic Variants G118V and R149I Affects Substate Binding and Catalysis. | 4 |
Citation
Dessen P
POLB (DNA polymerase beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41769/polb
