POP4 (POP4 homolog, ribonuclease P/MRP subunit)

2018-11-01  

Identity

HGNC
LOCATION
19q12
LOCUSID
ALIAS
RPP29
FUSION GENES

Other Information

Locus ID:

NCBI: 10775
MIM: 606114
HGNC: 30081
Ensembl: ENSG00000105171

Variants:

dbSNP: 10775
ClinVar: 10775
TCGA: ENSG00000105171
COSMIC: POP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105171ENST00000221770A0A0A0MQS4
ENSG00000105171ENST00000585603O95707
ENSG00000105171ENST00000586420K7ERD7
ENSG00000105171ENST00000586823K7EK50
ENSG00000105171ENST00000590688K7EQV2
ENSG00000105171ENST00000591061K7ESH8

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
RNA transportKEGGko03013
RNA transportKEGGhsa03013
Ribosome biogenesis in eukaryotesKEGGko03008
Ribosome biogenesis in eukaryotesKEGGhsa03008
Gene ExpressionREACTOMER-HSA-74160
tRNA processingREACTOMER-HSA-72306
tRNA processing in the nucleusREACTOMER-HSA-6784531

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
268428932016RNase P protein subunit Rpp29 represses histone H3.3 nucleosome deposition.7
284323562017A role of human RNase P subunits, Rpp29 and Rpp21, in homology directed-repair of double-strand breaks.5
299215822018Rpp29 regulates histone H3.3 chromatin assembly through transcriptional mechanisms.1
278103612017Functional characterization of archaeal homologs of human nuclear RNase P proteins Rpp21 and Rpp29 provides insights into the molecular basis of their cooperativity in catalysis.0

Citation

Dessen P

POP4 (POP4 homolog, ribonuclease P/MRP subunit)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57612/pop4