Identity
HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
OCT2,OTF2,Oct-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5452
MIM: 164176
HGNC: 9213
Ensembl: ENSG00000028277
Variants:
dbSNP: 5452
ClinVar: 5452
TCGA: ENSG00000028277
COSMIC: POU2F2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| RNA polymerase II transcribes snRNA genes | REACTOME | R-HSA-6807505 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38254723 | 2024 | Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates the Specificity of DNA Recognition by the POU-Domain Factors OCT1 and OCT2 in a Monomeric Configuration. | 0 |
| 38318853 | 2024 | POU2F2-mediated upregulation of lncRNA PTPRG-AS1 inhibits ferroptosis in breast cancer via miR-376c-3p/SLC7A11 axis. | 0 |
| 38254723 | 2024 | Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates the Specificity of DNA Recognition by the POU-Domain Factors OCT1 and OCT2 in a Monomeric Configuration. | 0 |
| 38318853 | 2024 | POU2F2-mediated upregulation of lncRNA PTPRG-AS1 inhibits ferroptosis in breast cancer via miR-376c-3p/SLC7A11 axis. | 0 |
| 36754897 | 2023 | OCT2 expression in histiocytoses. | 1 |
| 36849510 | 2023 | The MYC-regulated lncRNA LNROP (ENSG00000254887) enables MYC-driven cell proliferation by controlling the expression of OCT2. | 2 |
| 36754897 | 2023 | OCT2 expression in histiocytoses. | 1 |
| 36849510 | 2023 | The MYC-regulated lncRNA LNROP (ENSG00000254887) enables MYC-driven cell proliferation by controlling the expression of OCT2. | 2 |
| 35526483 | 2022 | CBX7 represses the POU2F2 to inhibit the PD-L1 expression and regulate the immune response in bladder cancer. | 2 |
| 35526483 | 2022 | CBX7 represses the POU2F2 to inhibit the PD-L1 expression and regulate the immune response in bladder cancer. | 2 |
| 33512466 | 2021 | OBF1 and Oct factors control the germinal center transcriptional program. | 11 |
| 33832481 | 2021 | POU2F2 promotes the proliferation and motility of lung cancer cells by activating AGO1. | 6 |
| 33931589 | 2021 | POU2F2 regulates glycolytic reprogramming and glioblastoma progression via PDPK1-dependent activation of PI3K/AKT/mTOR pathway. | 22 |
| 33965958 | 2021 | Long Non-Coding RNA ARAP1-AS1 Facilitates the Progression of Cervical Cancer by Regulating miR-149-3p and POU2F2. | 7 |
| 33512466 | 2021 | OBF1 and Oct factors control the germinal center transcriptional program. | 11 |
Citation
Dessen P
POU2F2 (POU class 2 homeobox 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46573/pou2f2
