Identity
HGNC
LOCATION
15q22.31
LOCUSID
ALIAS
B,CYP-S1,CYPB,HEL-S-39,OI9,SCYLP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5479
MIM: 123841
HGNC: 9255
Ensembl: ENSG00000166794
Variants:
dbSNP: 5479
ClinVar: 5479
TCGA: ENSG00000166794
COSMIC: PPIB
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166794 | ENST00000300026 | P23284 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Extracellular matrix organization | REACTOME | R-HSA-1474244 |
| Collagen formation | REACTOME | R-HSA-1474290 |
| Collagen biosynthesis and modifying enzymes | REACTOME | R-HSA-1650814 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31634494 | 2020 | Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication. | 49 |
| 32162654 | 2020 | Cyclophilins A and B oppositely regulate renal tubular epithelial cell phenotype. | 10 |
| 31634494 | 2020 | Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication. | 49 |
| 32162654 | 2020 | Cyclophilins A and B oppositely regulate renal tubular epithelial cell phenotype. | 10 |
| 30993352 | 2019 | Characterization of PPIB interaction in the P3H1 ternary complex and implications for its pathological mutations. | 5 |
| 31043353 | 2019 | Cyclophilin B promotes cell proliferation, migration, invasion and angiogenesis via regulating the STAT3 pathway in non-small cell lung cancer. | 10 |
| 30993352 | 2019 | Characterization of PPIB interaction in the P3H1 ternary complex and implications for its pathological mutations. | 5 |
| 31043353 | 2019 | Cyclophilin B promotes cell proliferation, migration, invasion and angiogenesis via regulating the STAT3 pathway in non-small cell lung cancer. | 10 |
| 30430148 | 2018 | A DR4 capturer with AKT siRNA for the synergetic enhancement of death receptor-mediated apoptosis. | 2 |
| 30430148 | 2018 | A DR4 capturer with AKT siRNA for the synergetic enhancement of death receptor-mediated apoptosis. | 2 |
| 28242392 | 2017 | Two novel mutations in the PPIB gene cause a rare pedigree of osteogenesis imperfecta type IX. | 8 |
| 28385890 | 2017 | Ziploc-ing the structure 2.0: Endoplasmic reticulum-resident peptidyl prolyl isomerases show different activities toward hydroxyproline. | 9 |
| 29146974 | 2017 | Human Cyclophilin B forms part of a multi-protein complex during erythrocyte invasion by Plasmodium falciparum. | 11 |
| 28242392 | 2017 | Two novel mutations in the PPIB gene cause a rare pedigree of osteogenesis imperfecta type IX. | 8 |
| 28385890 | 2017 | Ziploc-ing the structure 2.0: Endoplasmic reticulum-resident peptidyl prolyl isomerases show different activities toward hydroxyproline. | 9 |
Citation
Dessen P
PPIB (peptidylprolyl isomerase B)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46463/ppib
