PPM1H (protein phosphatase, Mg2+/Mn2+ dependent 1H)

2007-04-01  

Identity

HGNC
LOCATION
12q14.1
LOCUSID
ALIAS
ARHCL1,NERPP-2C,URCC2
FUSION GENES

Other Information

Locus ID:

NCBI: 57460
MIM: 616016
HGNC: 18583
Ensembl: ENSG00000111110

Variants:

dbSNP: 57460
ClinVar: 57460
TCGA: ENSG00000111110
COSMIC: PPM1H

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111110ENST00000228705Q9ULR3

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
207326272010Case-control genome-wide association study of attention-deficit/hyperactivity disorder.58
206593272010Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus.47
225866112011PPM1H is a p27 phosphatase implicated in trastuzumab resistance.15
180591822008Protein phosphatase 1H, overexpressed in colon adenocarcinoma, is associated with CSE1L.8
247320092014Specific control of BMP signaling and mesenchymal differentiation by cytoplasmic phosphatase PPM1H.7
316638532019PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins.5
275996702016Effect of PPM1H on malignant phenotype of human pancreatic cancer cells.4
309883942019Low tumour PPM1H indicates poor prognosis in colorectal cancer via activation of cancer-associated fibroblasts.2

Citation

Dessen P

PPM1H (protein phosphatase, Mg2+/Mn2+ dependent 1H)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46687/ppm1h