PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11)

2007-04-01  

Identity

HGNC
LOCATION
6p22.1
LOCUSID
ALIAS
CFAP255,HCG-V,HCGV,IPP3,TCTE5,TCTEX5
FUSION GENES

Other Information

Locus ID:

NCBI: 6992
MIM: 606670
HGNC: 9285
Ensembl: ENSG00000204619

Variants:

dbSNP: 6992
ClinVar: 6992
TCGA: ENSG00000204619
COSMIC: PPP1R11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204619ENST00000376758Q5SRK2
ENSG00000204619ENST00000376763Q5SRK2
ENSG00000204619ENST00000376765Q5SRK2
ENSG00000204619ENST00000376769Q5SRK2
ENSG00000204619ENST00000376772O60927
ENSG00000204619ENST00000376772A2BEK1
ENSG00000204619ENST00000376773Q5SRK2

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.51
176307782007A complex of catalytically inactive protein phosphatase-1 sandwiched between Sds22 and inhibitor-3.22
252983952014Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1.14
278059012016RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity.9
184507502008Protein phosphatase-1 inhibitor-3 is an in vivo target of caspase-3 and participates in the apoptotic response.8
189518792008Identification of the interaction sites of Inhibitor-3 for protein phosphatase-1.4

Citation

Dessen P

PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46838/ppp1r11