Identity
HGNC
LOCATION
14q32.33
LOCUSID
ALIAS
ASPP1,p53BP2-like,p85
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23368
MIM: 606455
HGNC: 14950
Ensembl: ENSG00000088808
Variants:
dbSNP: 23368
ClinVar: 23368
TCGA: ENSG00000088808
COSMIC: PPP1R13B
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32269211 | 2020 | ASPP1 deficiency promotes epithelial-mesenchymal transition, invasion and metastasis in colorectal cancer. | 7 |
| 32987288 | 2020 | Apoptosis stimulating protein of p53 (ASPP) 1 and ASPP2 m-RNA expression in oral cancer. | 2 |
| 32269211 | 2020 | ASPP1 deficiency promotes epithelial-mesenchymal transition, invasion and metastasis in colorectal cancer. | 7 |
| 32987288 | 2020 | Apoptosis stimulating protein of p53 (ASPP) 1 and ASPP2 m-RNA expression in oral cancer. | 2 |
| 28103919 | 2017 | Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study. | 3 |
| 28594407 | 2017 | EGR-1/ASPP1 inter-regulatory loop promotes apoptosis by inhibiting cyto-protective autophagy. | 8 |
| 28103919 | 2017 | Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study. | 3 |
| 28594407 | 2017 | EGR-1/ASPP1 inter-regulatory loop promotes apoptosis by inhibiting cyto-protective autophagy. | 8 |
| 27177208 | 2016 | A novel all-trans retinoic acid derivative 4-amino‑2‑trifluoromethyl-phenyl retinate inhibits the proliferation of human hepatocellular carcinoma HepG2 cells by inducing G0/G1 cell cycle arrest and apoptosis via upregulation of p53 and ASPP1 and downregulation of iASPP. | 13 |
| 27177208 | 2016 | A novel all-trans retinoic acid derivative 4-amino‑2‑trifluoromethyl-phenyl retinate inhibits the proliferation of human hepatocellular carcinoma HepG2 cells by inducing G0/G1 cell cycle arrest and apoptosis via upregulation of p53 and ASPP1 and downregulation of iASPP. | 13 |
| 25660448 | 2015 | The tumor suppressor proteins ASPP1 and ASPP2 interact with C-Nap1 and regulate centrosome linker reassembly. | 5 |
| 26595804 | 2015 | ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments. | 7 |
| 25660448 | 2015 | The tumor suppressor proteins ASPP1 and ASPP2 interact with C-Nap1 and regulate centrosome linker reassembly. | 5 |
| 26595804 | 2015 | ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments. | 7 |
| 23088536 | 2013 | Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins. | 17 |
Citation
Dessen P
PPP1R13B (protein phosphatase 1 regulatory subunit 13B)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41807/ppp1r13b
