PPP1R16B (protein phosphatase 1 regulatory subunit 16B)

2003-12-01  

Identity

HGNC
LOCATION
20q11.23
LOCUSID
ALIAS
ANKRD4,TIMAP
FUSION GENES

Other Information

Locus ID:

NCBI: 26051
MIM: 613275
HGNC: 15850
Ensembl: ENSG00000101445

Variants:

dbSNP: 26051
ClinVar: 26051
TCGA: ENSG00000101445
COSMIC: PPP1R16B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101445ENST00000299824Q96T49
ENSG00000101445ENST00000373331Q96T49

Expression (GTEx)

0
50
100
150

References

Pubmed IDYearTitleCitations
120551022002TIMAP, a novel CAAX box protein regulated by TGF-beta1 and expressed in endothelial cells.10
185869562008TIMAP is a positive regulator of pulmonary endothelial barrier function.10
250078732014TIMAP promotes angiogenesis by suppressing PTEN-mediated Akt inhibition in human glomerular endothelial cells.6
214668342011Characterization of the effect of TIMAP phosphorylation on its interaction with protein phosphatase 1.4
279391682017PKC mediated phosphorylation of TIMAP regulates PP1c activity and endothelial barrier function.3
219078352011TIMAP protects endothelial barrier from LPS-induced vascular leakage and is down-regulated by LPS.2
264979342015Elongation factor-1A1 is a novel substrate of the protein phosphatase 1-TIMAP complex.2
291405852017TIMAP, the versatile protein phosphatase 1 regulator in endothelial cells.2
278719512017Regulation of merlin by protein phosphatase 1-TIMAP and EBP50 in endothelial cells.1
268065472016TIMAP-protein phosphatase 1-complex controls endothelin-1 production via ECE-1 dephosphorylation.0

Citation

Dessen P

PPP1R16B (protein phosphatase 1 regulatory subunit 16B)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41809/ppp1r16b