PPP1R26 (protein phosphatase 1 regulatory subunit 26)

2011-10-01  

Identity

HGNC
PPP1R26
LOCATION
9q34.3
LOCUSID
9858
ALIAS
KIAA0649,NRBE3

Other Information

Locus ID:

NCBI: 9858
MIM: 614056
HGNC: 29089
Ensembl: ENSG00000196422

Variants:

dbSNP: 9858
ClinVar: 9858
TCGA: ENSG00000196422
COSMIC: PPP1R26

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196422ENST00000356818Q5T8A7
ENSG00000196422ENST00000401470Q5T8A7
ENSG00000196422ENST00000604351Q5T8A7
ENSG00000196422ENST00000605286Q5T8A7
ENSG00000196422ENST00000605660Q5T8A7

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
160539182005KIAA0649, a 1A6/DRIM-interacting protein with the oncogenic potential.4
264425852015A Novel Retinoblastoma Protein (RB) E3 Ubiquitin Ligase (NRBE3) Promotes RB Degradation and Is Transcriptionally Regulated by E2F1 Transcription Factor.3
302624342018NRBE3 promotes metastasis of breast cancer by down-regulating E-cadherin expression.2

Citation

Dessen P

PPP1R26 (protein phosphatase 1 regulatory subunit 26)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52419/ppp1r26