Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5506
MIM: 600917
HGNC: 9291
Ensembl: ENSG00000154415
Variants:
dbSNP: 5506
ClinVar: 5506
TCGA: ENSG00000154415
COSMIC: PPP1R3A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000154415 | ENST00000284601 | Q16821 |
| ENSG00000154415 | ENST00000284602 | Q16821 |
| ENSG00000154415 | ENST00000449795 | C9JZB3 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Insulin signaling pathway | KEGG | ko04910 |
| Insulin signaling pathway | KEGG | hsa04910 |
| Insulin resistance | KEGG | hsa04931 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37642261 | 2023 | Decreased PPP1R3G in pre-eclampsia impairs human trophoblast invasion and migration via Akt/MMP-9 signaling pathway. | 0 |
| 37642261 | 2023 | Decreased PPP1R3G in pre-eclampsia impairs human trophoblast invasion and migration via Akt/MMP-9 signaling pathway. | 0 |
| 31235787 | 2019 | Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure. | 15 |
| 31235787 | 2019 | Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure. | 15 |
| 29948331 | 2018 | Whole-exome sequencing in maya indigenous families: variant in PPP1R3A is associated with type 2 diabetes. | 7 |
| 29948331 | 2018 | Whole-exome sequencing in maya indigenous families: variant in PPP1R3A is associated with type 2 diabetes. | 7 |
| 27587435 | 2017 | Molecular Differences between Screen-Detected and Interval Breast Cancers Are Largely Explained by PAM50 Subtypes. | 8 |
| 27587435 | 2017 | Molecular Differences between Screen-Detected and Interval Breast Cancers Are Largely Explained by PAM50 Subtypes. | 8 |
| 23359326 | 2013 | A novel interaction between hScrib and PP1γ downregulates ERK signaling and suppresses oncogene-induced cell transformation. | 16 |
| 23359326 | 2013 | A novel interaction between hScrib and PP1γ downregulates ERK signaling and suppresses oncogene-induced cell transformation. | 16 |
| 19056482 | 2009 | Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome. | 6 |
| 19578796 | 2009 | Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. | 8 |
| 19056482 | 2009 | Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome. | 6 |
| 19578796 | 2009 | Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. | 8 |
| 18232732 | 2008 | A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice. | 25 |
Citation
Dessen P
PPP1R3A (protein phosphatase 1 regulatory subunit 3A)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41810/ppp1r3a
