Atlas of Genetics and Cytogenetics in Oncology and Haematology

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PPP2R3C (protein phosphatase 2 regulatory subunit B''gamma)

Identity

Alias_namesC14orf10
chromosome 14 open reading frame 10
protein phosphatase 2 (formerly 2A), regulatory subunit B''
Alias_symbol (synonym)FLJ20644
G4-1
G5PR
Other aliasG5pr
GDRM
SPGF36
HGNC (Hugo) PPP2R3C
LocusID (NCBI) 55012
Atlas_Id 72154
Location 14q13.2  [Link to chromosome band 14q13]
Location_base_pair Starts at 35085468 and ends at 35122542 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PPP2R3C (14q13.2) / NFKBIA (14q13.2)WARS (14q32.2) / PPP2R3C (14q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PPP2R3C   17485
Cards
Entrez_Gene (NCBI)PPP2R3C  55012  protein phosphatase 2 regulatory subunit B''gamma
AliasesC14orf10; G4-1; G5pr; GDRM; 
SPGF36
GeneCards (Weizmann)PPP2R3C
Ensembl hg19 (Hinxton)ENSG00000092020 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000092020 [Gene_View]  ENSG00000092020 [Sequence]  chr14:35085468-35122542 [Contig_View]  PPP2R3C [Vega]
ICGC DataPortalENSG00000092020
TCGA cBioPortalPPP2R3C
AceView (NCBI)PPP2R3C
Genatlas (Paris)PPP2R3C
WikiGenes55012
SOURCE (Princeton)PPP2R3C
Genetics Home Reference (NIH)PPP2R3C
Genomic and cartography
GoldenPath hg38 (UCSC)PPP2R3C  -     chr14:35085468-35122542 -  14q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP2R3C  -     14q13.2   [Description]    (hg19-Feb_2009)
GoldenPathPPP2R3C - 14q13.2 [CytoView hg19]  PPP2R3C - 14q13.2 [CytoView hg38]
ImmunoBaseENSG00000092020
Mapping of homologs : NCBIPPP2R3C [Mapview hg19]  PPP2R3C [Mapview hg38]
OMIM615902   618419   618420   
Gene and transcription
Genbank (Entrez)AA603611 AK000651 AK225447 AK225512 AK293717
RefSeq transcript (Entrez)NM_001305155 NM_001305156 NM_017917
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPP2R3C
Cluster EST : UnigeneHs.621667 [ NCBI ]
CGAP (NCI)Hs.621667
Alternative Splicing GalleryENSG00000092020
Gene ExpressionPPP2R3C [ NCBI-GEO ]   PPP2R3C [ EBI - ARRAY_EXPRESS ]   PPP2R3C [ SEEK ]   PPP2R3C [ MEM ]
Gene Expression Viewer (FireBrowse)PPP2R3C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55012
GTEX Portal (Tissue expression)PPP2R3C
Human Protein AtlasENSG00000092020-PPP2R3C [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969Q6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969Q6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969Q6
Splice isoforms : SwissVarQ969Q6
PhosPhoSitePlusQ969Q6
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PPP2R3C
DMDM Disease mutations55012
Blocks (Seattle)PPP2R3C
SuperfamilyQ969Q6
Human Protein Atlas [tissue]ENSG00000092020-PPP2R3C [tissue]
Peptide AtlasQ969Q6
HPRD12622
IPIIPI00550228   IPI00827645   IPI01025135   IPI01026328   IPI01026452   IPI01024789   IPI01025029   IPI01025260   IPI01025356   IPI00790787   IPI01025590   IPI01025598   IPI01025695   IPI01026335   
Protein Interaction databases
DIP (DOE-UCLA)Q969Q6
IntAct (EBI)Q969Q6
FunCoupENSG00000092020
BioGRIDPPP2R3C
STRING (EMBL)PPP2R3C
ZODIACPPP2R3C
Ontologies - Pathways
QuickGOQ969Q6
Ontology : AmiGOmicrotubule cytoskeleton organization  B cell homeostasis  regulation of antimicrobial humoral response  protein binding  nucleus  Golgi apparatus  centrosome  centrosome  spindle  cytosol  cortical cytoskeleton organization  activation of protein kinase activity  regulation of dephosphorylation  T cell homeostasis  positive regulation of B cell differentiation  metal ion binding  spleen development  regulation of mitochondrial depolarization  
Ontology : EGO-EBImicrotubule cytoskeleton organization  B cell homeostasis  regulation of antimicrobial humoral response  protein binding  nucleus  Golgi apparatus  centrosome  centrosome  spindle  cytosol  cortical cytoskeleton organization  activation of protein kinase activity  regulation of dephosphorylation  T cell homeostasis  positive regulation of B cell differentiation  metal ion binding  spleen development  regulation of mitochondrial depolarization  
NDEx NetworkPPP2R3C
Atlas of Cancer Signalling NetworkPPP2R3C
Wikipedia pathwaysPPP2R3C
Orthology - Evolution
OrthoDB55012
GeneTree (enSembl)ENSG00000092020
Phylogenetic Trees/Animal Genes : TreeFamPPP2R3C
HOGENOMQ969Q6
Homologs : HomoloGenePPP2R3C
Homology/Alignments : Family Browser (UCSC)PPP2R3C
Gene fusions - Rearrangements
Fusion : QuiverPPP2R3C
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP2R3C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP2R3C
dbVarPPP2R3C
ClinVarPPP2R3C
1000_GenomesPPP2R3C 
Exome Variant ServerPPP2R3C
ExAC (Exome Aggregation Consortium)ENSG00000092020
GNOMAD BrowserENSG00000092020
Varsome BrowserPPP2R3C
Genetic variants : HAPMAP55012
Genomic Variants (DGV)PPP2R3C [DGVbeta]
DECIPHERPPP2R3C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP2R3C 
Mutations
ICGC Data PortalPPP2R3C 
TCGA Data PortalPPP2R3C 
Broad Tumor PortalPPP2R3C
OASIS PortalPPP2R3C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP2R3C  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPPP2R3C
Mutations and Diseases : HGMDPPP2R3C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP2R3C
DgiDB (Drug Gene Interaction Database)PPP2R3C
DoCM (Curated mutations)PPP2R3C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP2R3C (select a term)
intoGenPPP2R3C
Cancer3DPPP2R3C(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615902    618419    618420   
Orphanet
DisGeNETPPP2R3C
MedgenPPP2R3C
Genetic Testing Registry PPP2R3C
NextProtQ969Q6 [Medical]
TSGene55012
GENETestsPPP2R3C
Target ValidationPPP2R3C
Huge Navigator PPP2R3C [HugePedia]
snp3D : Map Gene to Disease55012
BioCentury BCIQPPP2R3C
ClinGenPPP2R3C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55012
Chemical/Pharm GKB GenePA162400008
Clinical trialPPP2R3C
Miscellaneous
canSAR (ICR)PPP2R3C (select the gene name)
DataMed IndexPPP2R3C
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP2R3C
EVEXPPP2R3C
GoPubMedPPP2R3C
iHOPPPP2R3C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 16:01:50 CEST 2019
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