Identity
HGNC
LOCATION
10q22.2
LOCUSID
ALIAS
CALNA2,CALNB,CNA2,PP2Bbeta
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5532
MIM: 114106
HGNC: 9315
Ensembl: ENSG00000107758
Variants:
dbSNP: 5532
ClinVar: 5532
TCGA: ENSG00000107758
COSMIC: PPP3CB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA248 | NFKB1 | Gene | Pathway | associated | 23922006 | ||
| PA296 | RELA | Gene | Pathway | associated | 23922006 | ||
| PA31582 | NFATC1 | Gene | Pathway | associated | 23922006 | ||
| PA31583 | NFATC2 | Gene | Pathway | associated | 23922006 | ||
| PA31584 | NFATC4 | Gene | Pathway | associated | 23922006 | ||
| PA31600 | NFKB2 | Gene | Pathway | associated | 23922006 | ||
| PA34321 | REL | Gene | Pathway | associated | 23922006 | ||
| PA34322 | RELB | Gene | Pathway | associated | 23922006 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30457174 | 2019 | PPP3CB contributes to poor prognosis through activating nuclear factor of activated T-cells signaling in neuroblastoma. | 6 |
| 30641937 | 2019 | PPP3CB Inhibits Migration of G401 Cells via Regulating Epithelial-to-Mesenchymal Transition and Promotes G401 Cells Growth. | 3 |
| 30457174 | 2019 | PPP3CB contributes to poor prognosis through activating nuclear factor of activated T-cells signaling in neuroblastoma. | 6 |
| 30641937 | 2019 | PPP3CB Inhibits Migration of G401 Cells via Regulating Epithelial-to-Mesenchymal Transition and Promotes G401 Cells Growth. | 3 |
| 27907007 | 2016 | Exploring Regulatory Mechanisms of Atrial Myocyte Hypertrophy of Mitral Regurgitation through Gene Expression Profiling Analysis: Role of NFAT in Cardiac Hypertrophy. | 3 |
| 27907007 | 2016 | Exploring Regulatory Mechanisms of Atrial Myocyte Hypertrophy of Mitral Regurgitation through Gene Expression Profiling Analysis: Role of NFAT in Cardiac Hypertrophy. | 3 |
| 25286016 | 2014 | Oxidation-induced conformational changes in calcineurin determined by covalent labeling and tandem mass spectrometry. | 8 |
| 25286016 | 2014 | Oxidation-induced conformational changes in calcineurin determined by covalent labeling and tandem mass spectrometry. | 8 |
| 23888774 | 2013 | [Expression profile of calcineurin pathway genes in myocardium tissues in relation to ischemic heart remodeling in humans]. | 2 |
| 23888774 | 2013 | [Expression profile of calcineurin pathway genes in myocardium tissues in relation to ischemic heart remodeling in humans]. | 2 |
| 22739212 | 2012 | Calcineurin expression and activity is regulated by the intracellular redox status and under hypertension in human neutrophils. | 1 |
| 22739212 | 2012 | Calcineurin expression and activity is regulated by the intracellular redox status and under hypertension in human neutrophils. | 1 |
| 21233773 | 2011 | Are calcineurin genes associated with athletic status? A function, replication study. | 10 |
| 21423799 | 2011 | Expression of a constitutively active calcineurin encoded by an intron-retaining mRNA in follicular keratinocytes. | 6 |
| 21531385 | 2011 | ANXA7, PPP3CB, DNAJC9, and ZMYND17 genes at chromosome 10q22 associated with the subgroup of schizophrenia with deficits in attention and executive function. | 8 |
Citation
Dessen P
PPP3CB (protein phosphatase 3 catalytic subunit beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41823/ppp3cb
