PRB2 (proline rich protein BstNI subfamily 2)

2014-11-01  

Identity

HGNC
PRB2
LOCATION
12p13.2
LOCUSID
653247
ALIAS
IB-9,PRPPRB1,Ps,cP7
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 653247
MIM: 168810
HGNC: 9338
Ensembl: ENSG00000121335

Variants:

dbSNP: 653247
ClinVar: 653247
TCGA: ENSG00000121335
COSMIC: PRB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121335ENST00000389362P02812
ENSG00000121335ENST00000565533H3BR58

Expression (GTEx)

0
1
2
3
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Salivary secretionKEGGko04970
Salivary secretionKEGGhsa04970

References

Pubmed IDYearTitleCitations
150771612004Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A.27
252054582015pRb2/p130 localizes to the cytoplasm in diffuse gastric cancer.3
159234242005The regulation of ER-alpha transcription by pRb2/p130 in breast cancer.1

Citation

Dessen P

PRB2 (proline rich protein BstNI subfamily 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72189/prb2