PRDX5 (peroxiredoxin 5)

2007-02-01  

Identity

HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
ACR1,AOEB166,B166,HEL-S-55,PLP,PMP20,PRDX6,PRXV,SBBI10,prx-V
FUSION GENES

Other Information

Locus ID:

NCBI: 25824
MIM: 606583
HGNC: 9355
Ensembl: ENSG00000126432

Variants:

dbSNP: 25824
ClinVar: 25824
TCGA: ENSG00000126432
COSMIC: PRDX5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126432ENST00000265462P30044
ENSG00000126432ENST00000347941P30044
ENSG00000126432ENST00000352435P30044

Expression (GTEx)

0
100
200
300
400
500
600
700

Pathways

PathwaySourceExternal ID
PeroxisomeKEGGko04146
PeroxisomeKEGGhsa04146
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
TP53 Regulates Metabolic GenesREACTOMER-HSA-5628897
Cellular responses to stressREACTOMER-HSA-2262752
Detoxification of Reactive Oxygen SpeciesREACTOMER-HSA-3299685

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
374959082024Selenoprotein P, peroxiredoxin-5, renalase, and total antioxidant status in patients with suspected obstructive sleep apnea.0
381157652024Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer.3
374959082024Selenoprotein P, peroxiredoxin-5, renalase, and total antioxidant status in patients with suspected obstructive sleep apnea.0
381157652024Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer.3
339695952023Peroxiredoxin 5 is involved in cancer cell invasion and tumor growth of oral squamous cell carcinoma.1
374437472023Prdx5 in the Regulation of Tuberous Sclerosis Complex Mutation-Induced Signaling Mechanisms.0
380101882023[Thioredoxin-reductase in fibroblasts of human dermis in the process of aging.].0
339695952023Peroxiredoxin 5 is involved in cancer cell invasion and tumor growth of oral squamous cell carcinoma.1
374437472023Prdx5 in the Regulation of Tuberous Sclerosis Complex Mutation-Induced Signaling Mechanisms.0
380101882023[Thioredoxin-reductase in fibroblasts of human dermis in the process of aging.].0
348889382022Antioxidant enzyme peroxiredoxin 5 regulates cyst growth and ciliogenesis via modulating Plk1 stability.5
355467382022Knockdown of Peroxiredoxin V increased the cytotoxicity of non-thermal plasma-treated culture medium to A549 cells.2
348889382022Antioxidant enzyme peroxiredoxin 5 regulates cyst growth and ciliogenesis via modulating Plk1 stability.5
355467382022Knockdown of Peroxiredoxin V increased the cytotoxicity of non-thermal plasma-treated culture medium to A549 cells.2
334161062021ROS‑mediated hypomethylation of PRDX5 promotes STAT3 binding and activates the Nrf2 signaling pathway in NSCLC.5

Citation

Dessen P

PRDX5 (peroxiredoxin 5)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46272/prdx5