Identity
HGNC
LOCATION
11q12.1
LOCUSID
ALIAS
BMPG,MBP,MBP1,proMBP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5553
MIM: 605601
HGNC: 9362
Ensembl: ENSG00000186652
Variants:
dbSNP: 5553
ClinVar: 5553
TCGA: ENSG00000186652
COSMIC: PRG2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186652 | ENST00000311862 | P13727 |
| ENSG00000186652 | ENST00000525955 | P13727 |
| ENSG00000186652 | ENST00000533605 | P13727 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Asthma | KEGG | ko05310 |
| Asthma | KEGG | hsa05310 |
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37278449 | 2023 | Comparison of pancreatic enzyme abnormalities and protease-activated receptor-2-positive eosinophils in the duodenum of patients with functional dyspepsia-irritable bowel syndrome overlap with functional dyspepsia alone in Asian populations. | 0 |
| 37278449 | 2023 | Comparison of pancreatic enzyme abnormalities and protease-activated receptor-2-positive eosinophils in the duodenum of patients with functional dyspepsia-irritable bowel syndrome overlap with functional dyspepsia alone in Asian populations. | 0 |
| 33689807 | 2021 | Development and application of novel immunoassays for eosinophil granule major basic proteins to evaluate eosinophilia and myeloproliferative disorders. | 1 |
| 33982062 | 2021 | PRG2 and AQPEP are misexpressed in fetal membranes in placenta previa and percreta†. | 2 |
| 33689807 | 2021 | Development and application of novel immunoassays for eosinophil granule major basic proteins to evaluate eosinophilia and myeloproliferative disorders. | 1 |
| 33982062 | 2021 | PRG2 and AQPEP are misexpressed in fetal membranes in placenta previa and percreta†. | 2 |
| 31595373 | 2020 | Mechanism of atopic cataract caused by eosinophil granule major basic protein. | 2 |
| 31595373 | 2020 | Mechanism of atopic cataract caused by eosinophil granule major basic protein. | 2 |
| 29936783 | 2018 | Re-Expression of Bone Marrow Proteoglycan-2 by 5-Azacytidine is associated with STAT3 Inactivation and Sensitivity Response to Imatinib in Resistant CML Cells. | 9 |
| 29936783 | 2018 | Re-Expression of Bone Marrow Proteoglycan-2 by 5-Azacytidine is associated with STAT3 Inactivation and Sensitivity Response to Imatinib in Resistant CML Cells. | 9 |
| 25266917 | 2015 | An immunologic test for chronic rhinosinusitis based on free intranasal eosinophilic major basic protein. | 0 |
| 25728769 | 2015 | Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. | 43 |
| 25266917 | 2015 | An immunologic test for chronic rhinosinusitis based on free intranasal eosinophilic major basic protein. | 0 |
| 25728769 | 2015 | Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. | 43 |
| 24814827 | 2014 | Expression levels of eosinophil granule protein mRNAs in induced sputum reflect airway hyperresponsiveness and airflow limitation. | 4 |
Citation
Dessen P
PRG2 (proteoglycan 2, pro eosinophil major basic protein)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41841/prg2
