Identity
HGNC
LOCATION
12q12
LOCUSID
ALIAS
EPM1B,RILP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 144165
MIM: 608500
HGNC: 17019
Ensembl: ENSG00000139174
Variants:
dbSNP: 144165
ClinVar: 144165
TCGA: ENSG00000139174
COSMIC: PRICKLE1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34001134 | 2021 | PRICKLE1, a Wnt/PCP signaling component, is overexpressed and associated with inferior prognosis in acute myeloid leukemia. | 12 |
| 34001134 | 2021 | PRICKLE1, a Wnt/PCP signaling component, is overexpressed and associated with inferior prognosis in acute myeloid leukemia. | 12 |
| 30564977 | 2019 | Sudden unexpected death with rare compound heterozygous variants in PRICKLE1. | 2 |
| 30971775 | 2019 | ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer. | 9 |
| 30564977 | 2019 | Sudden unexpected death with rare compound heterozygous variants in PRICKLE1. | 2 |
| 30971775 | 2019 | ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer. | 9 |
| 30345727 | 2018 | PRICKLE1-related early onset epileptic encephalopathy. | 6 |
| 30345727 | 2018 | PRICKLE1-related early onset epileptic encephalopathy. | 6 |
| 27036398 | 2016 | Planar cell polarity gene expression correlates with tumor cell viability and prognostic outcome in neuroblastoma. | 15 |
| 27184734 | 2016 | PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2. | 42 |
| 27378169 | 2016 | Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5β complex in migrating cells. | 23 |
| 27036398 | 2016 | Planar cell polarity gene expression correlates with tumor cell viability and prognostic outcome in neuroblastoma. | 15 |
| 27184734 | 2016 | PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2. | 42 |
| 27378169 | 2016 | Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5β complex in migrating cells. | 23 |
| 24312498 | 2013 | PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders. | 28 |
Citation
Dessen P
PRICKLE1 (prickle planar cell polarity protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46033/prickle1
