Identity
HGNC
LOCATION
10q11.23
LOCUSID
ALIAS
AAT8,PKG,PKG1,PRKG1B,PRKGR1B,cGK,cGK
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5592
MIM: 176894
HGNC: 9414
Ensembl: ENSG00000185532
Variants:
dbSNP: 5592
ClinVar: 5592
TCGA: ENSG00000185532
COSMIC: PRKG1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38678552 | 2024 | Anti-NSCLC role of SCN4B by negative regulation of the cGMP-PKG pathway: Integrated utilization of bioinformatics analysis and in vitro assay validation. | 0 |
| 38678552 | 2024 | Anti-NSCLC role of SCN4B by negative regulation of the cGMP-PKG pathway: Integrated utilization of bioinformatics analysis and in vitro assay validation. | 0 |
| 36653376 | 2023 | Increased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway. | 6 |
| 36653376 | 2023 | Increased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway. | 6 |
| 36614110 | 2022 | Downexpression of miR-200c-3p Contributes to Achalasia Disease by Targeting the PRKG1 Gene. | 1 |
| 36614110 | 2022 | Downexpression of miR-200c-3p Contributes to Achalasia Disease by Targeting the PRKG1 Gene. | 1 |
| 32773598 | 2021 | Nociceptor-localized cGMP-dependent protein kinase I is a critical generator for central sensitization and neuropathic pain. | 15 |
| 33628342 | 2021 | Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes. | 5 |
| 34400180 | 2021 | Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G. | 2 |
| 32773598 | 2021 | Nociceptor-localized cGMP-dependent protein kinase I is a critical generator for central sensitization and neuropathic pain. | 15 |
| 33628342 | 2021 | Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes. | 5 |
| 34400180 | 2021 | Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G. | 2 |
| 31911580 | 2020 | O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth. | 97 |
| 32096871 | 2020 | Expression profiles of PRKG1, SDF2L1 and PPP1R12A are predictive and prognostic factors for therapy response and survival in high-grade serous ovarian cancer. | 9 |
| 32506052 | 2020 | A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP. | 5 |
Citation
Dessen P
PRKG1 (protein kinase cGMP-dependent 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41864/prkg1
