PRM2 (protamine 2)

2007-07-01  

Identity

HGNC
LOCATION
16p13.13
LOCUSID
ALIAS
CT94.2

Other Information

Locus ID:

NCBI: 5620
MIM: 182890
HGNC: 9448
Ensembl: ENSG00000122304

Variants:

dbSNP: 5620
ClinVar: 5620
TCGA: ENSG00000122304
COSMIC: PRM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122304ENST00000241808P04554
ENSG00000122304ENST00000241808Q1LZN1
ENSG00000122304ENST00000435245P04554

Expression (GTEx)

0
5000
10000
15000
20000
25000

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
125243522002Accelerated protein evolution and origins of human-specific features: Foxp2 as an example.73
203786152010Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent.40
170115552006Sperm protamine 1/protamine 2 ratios are related to in vitro fertilization pregnancy rates and predictive of fertilization ability.24
166324642006Protamine 2 precursors, protamine 1/protamine 2 ratio, DNA integrity and other sperm parameters in infertile patients.23
184781562008Characterization of nucleohistone and nucleoprotamine components in the mature human sperm nucleus.17
125691752003Single nucleotide polymorphisms in the protamine-1 and -2 genes of fertile and infertile human male populations.16
125691752003Single nucleotide polymorphisms in the protamine-1 and -2 genes of fertile and infertile human male populations.16
156704152004Effect of protamine-2 deficiency on ICSI outcome.14
169898272006Identification of novel polymorphisms in the nuclear protein genes and their relationship with human sperm protamine deficiency and severe male infertility.14
169898272006Identification of novel polymorphisms in the nuclear protein genes and their relationship with human sperm protamine deficiency and severe male infertility.14

Citation

Dessen P

PRM2 (protamine 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47641/prm2