Identity
HGNC
LOCATION
22q11.21
LOCUSID
ALIAS
HSPOX2,PIG6,POX,PRODH1,PRODH2,TP53I6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5625
MIM: 606810
HGNC: 9453
Ensembl: ENSG00000100033
Variants:
dbSNP: 5625
ClinVar: 5625
TCGA: ENSG00000100033
COSMIC: PRODH
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38255788 | 2024 | Proline Dehydrogenase (PRODH) Is Expressed in Lung Adenocarcinoma and Modulates Cell Survival and 3D Growth by Inducing Cellular Senescence. | 1 |
| 38255788 | 2024 | Proline Dehydrogenase (PRODH) Is Expressed in Lung Adenocarcinoma and Modulates Cell Survival and 3D Growth by Inducing Cellular Senescence. | 1 |
| 37564635 | 2023 | Prognostic and immunomodulatory roles of schizophrenia-associated genes HTR2A, COMT, and PRODH in pan-cancer analysis and glioma survival prediction model. | 3 |
| 37564635 | 2023 | Prognostic and immunomodulatory roles of schizophrenia-associated genes HTR2A, COMT, and PRODH in pan-cancer analysis and glioma survival prediction model. | 3 |
| 35367090 | 2022 | Impact of COMT, PRODH and DISC1 Genetic Variants on Cognitive Performance of Patients with Schizophrenia. | 2 |
| 35367090 | 2022 | Impact of COMT, PRODH and DISC1 Genetic Variants on Cognitive Performance of Patients with Schizophrenia. | 2 |
| 34944532 | 2021 | Metformin Treatment or PRODH/POX-Knock out Similarly Induces Apoptosis by Reprograming of Amino Acid Metabolism, TCA, Urea Cycle and Pentose Phosphate Pathway in MCF-7 Breast Cancer Cells. | 6 |
| 34944532 | 2021 | Metformin Treatment or PRODH/POX-Knock out Similarly Induces Apoptosis by Reprograming of Amino Acid Metabolism, TCA, Urea Cycle and Pentose Phosphate Pathway in MCF-7 Breast Cancer Cells. | 6 |
| 31933109 | 2020 | Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to targeted cancer therapy. | 26 |
| 31933109 | 2020 | Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to targeted cancer therapy. | 26 |
| 30867130 | 2019 | Exercise Reveals Proline Dehydrogenase as a Potential Target in Heart Failure. | 9 |
| 30867130 | 2019 | Exercise Reveals Proline Dehydrogenase as a Potential Target in Heart Failure. | 9 |
| 28264926 | 2017 | Proline dehydrogenase promotes senescence through the generation of reactive oxygen species. | 36 |
| 28685754 | 2017 | Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions. | 203 |
| 28942439 | 2017 | Functional Consequences of Intracellular Proline Levels Manipulation Affecting PRODH/POX-Dependent Pro-Apoptotic Pathways in a Novel in Vitro Cell Culture Model. | 15 |
Citation
Dessen P
PRODH (proline dehydrogenase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41873/prodh
