PROM2 (prominin 2)

2007-12-01  

Identity

HGNC
PROM2
LOCATION
2q11.1
LOCUSID
150696
ALIAS
PROML2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 150696
MIM: 617160
HGNC: 20685
Ensembl: ENSG00000155066

Variants:

dbSNP: 150696
ClinVar: 150696
TCGA: ENSG00000155066
COSMIC: PROM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000155066ENST00000317620Q8N271
ENSG00000155066ENST00000317668Q8N271
ENSG00000155066ENST00000403131Q8N271
ENSG00000155066ENST00000431567F8WDW5

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
125141872003Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins.31
171458112006Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes.22
197248562009Effect of CD133/prominin-1 antisense oligodeoxynucleotide on in vitro growth characteristics of Huh-7 human hepatocarcinoma cells and U251 human glioma cells.11
185369292008Robust expression of Prominin-2 all along the adult male reproductive system and urinary bladder.6
203333962010Prominin-2 is a novel marker of distal tubules and collecting ducts of the human and murine kidney.6
317356632019Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export.4
235833802013Prominin-2 expression increases protrusions, decreases caveolae and inhibits Cdc42 dependent fluid phase endocytosis.3

Citation

Dessen P

PROM2 (prominin 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49882/prom2