Identity
HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
ANT-1,ANT1,C20orf14,Prp6,RP60,SNRNP102,TOM,U5-102K,hPrp6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 24148
MIM: 613979
HGNC: 15860
Ensembl: ENSG00000101161
Variants:
dbSNP: 24148
ClinVar: 24148
TCGA: ENSG00000101161
COSMIC: PRPF6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101161 | ENST00000266079 | O94906 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38139438 | 2023 | Pathogenic Variants in USH1G/SANS Alter Protein Interaction with Pre-RNA Processing Factors PRPF6 and PRPF31 of the Spliceosome. | 0 |
| 38139438 | 2023 | Pathogenic Variants in USH1G/SANS Alter Protein Interaction with Pre-RNA Processing Factors PRPF6 and PRPF31 of the Spliceosome. | 0 |
| 33390843 | 2021 | PRPF6 promotes androgen receptor/androgen receptor-variant 7 actions in castration-resistant prostate cancer cells. | 8 |
| 37303939 | 2021 | PRPF6 promotes metastasis and paclitaxel resistance of ovarian cancer via SNHG16/CEBPB/GATA3 axis. | 1 |
| 33390843 | 2021 | PRPF6 promotes androgen receptor/androgen receptor-variant 7 actions in castration-resistant prostate cancer cells. | 8 |
| 37303939 | 2021 | PRPF6 promotes metastasis and paclitaxel resistance of ovarian cancer via SNHG16/CEBPB/GATA3 axis. | 1 |
| 32745318 | 2020 | Splicing factor PRPF6 upregulates oncogenic androgen receptor signaling pathway in hepatocellular carcinoma. | 9 |
| 32745318 | 2020 | Splicing factor PRPF6 upregulates oncogenic androgen receptor signaling pathway in hepatocellular carcinoma. | 9 |
| 24788092 | 2014 | An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth. | 53 |
| 24788092 | 2014 | An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth. | 53 |
| 21549338 | 2011 | A missense mutation in PRPF6 causes impairment of pre-mRNA splicing and autosomal-dominant retinitis pigmentosa. | 62 |
| 21549338 | 2011 | A missense mutation in PRPF6 causes impairment of pre-mRNA splicing and autosomal-dominant retinitis pigmentosa. | 62 |
| 20118938 | 2010 | Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation. | 45 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20118938 | 2010 | Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation. | 45 |
Citation
Dessen P
PRPF6 (pre-mRNA processing factor 6)
Atlas Genet Cytogenet Oncol Haematol. 2008-12-01
Online version: http://atlasgeneticsoncology.org/gene/50576/prpf6
