PRR13 (proline rich 13)

2003-12-01  

Identity

HGNC
PRR13
LOCATION
12q13.13
LOCUSID
54458
ALIAS
TXR1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54458
MIM: 610459
HGNC: 24528
Ensembl: ENSG00000205352

Variants:

dbSNP: 54458
ClinVar: 54458
TCGA: ENSG00000205352
COSMIC: PRR13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205352ENST00000379786Q9NZ81
ENSG00000205352ENST00000429243Q9NZ81
ENSG00000205352ENST00000429243A0A024RB45
ENSG00000205352ENST00000546581F8VP70
ENSG00000205352ENST00000547368F8VZP4
ENSG00000205352ENST00000549068F8VWB5
ENSG00000205352ENST00000549135Q9NZ81
ENSG00000205352ENST00000549135A0A024RB45
ENSG00000205352ENST00000549581Q9NZ81
ENSG00000205352ENST00000549740F8VU40
ENSG00000205352ENST00000549924Q9NZ81
ENSG00000205352ENST00000549924A0A024RB45
ENSG00000205352ENST00000551003F8VRX0
ENSG00000205352ENST00000551945F8W1R5

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
194358352009Tumoral expression of TXR1 and TSP1 predicts overall survival of patients with lung adenocarcinoma treated with first-line docetaxel-gemcitabine regimen.18
211574492011Correlation of BRCA1, TXR1 and TSP1 mRNA expression with treatment outcome to docetaxel-based first-line chemotherapy in patients with advanced/metastatic non-small-cell lung cancer.17
243627942014Txr1: an important factor in oxaliplatin resistance in gastric cancer.6
277792442017Predictive value of ATP7b, BRCA1, BRCA2, PARP1, UIMC1 (RAP80), HOXA9, DAXX, TXN (TRX1), THBS1 (TSP1) and PRR13 (TXR1) genes in patients with epithelial ovarian cancer who received platinum-taxane first-line therapy.4
283451252018New Clues in the Malignant Progression of Glioblastoma: Can the Thioredoxin System Play a Role?2
306500692019Taxol-Resistant Gene 1 (Txr1) Mediates Oxaliplatin Resistance by Inducing Autophagy in Human Nasopharyngeal Carcinoma Cells.0

Citation

Dessen P

PRR13 (proline rich 13)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40318/prr13