PRSS27 (serine protease 27)

2014-11-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
CAPH2,MPN
FUSION GENES

Other Information

Locus ID:

NCBI: 83886
MIM: 608018
HGNC: 15475
Ensembl: ENSG00000172382

Variants:

dbSNP: 83886
ClinVar: 83886
TCGA: ENSG00000172382
COSMIC: PRSS27

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172382ENST00000302641Q9BQR3
ENSG00000172382ENST00000562249H3BSV0
ENSG00000172382ENST00000565903H3BSV0

Expression (GTEx)

0
50
100
150
200
250
300
350

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
189482662009The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyperproliferative epidermis of psoriasis and regenerating wounds.14
124413432003Structure and activity of human pancreasin, a novel tryptic serine peptidase expressed primarily by the pancreas.10
234475382013Mutational tail loss is an evolutionary mechanism for liberating marapsins and other type I serine proteases from transmembrane anchors.2

Citation

Dessen P

PRSS27 (serine protease 27)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72304/prss27