PRSS50 (serine protease 50)

2009-11-01 Affiliation

HGNC

PRSS50

LOCATION

3p21.31

LOCUSID

29122

ALIAS

CT20,TSP50

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

dbSNP: 29122
ClinVar: 29122
TCGA: ENSG00000283706
COSMIC: PRSS50

Gene ID	Transcript ID	Uniprot
ENSG00000283706	ENST00000315170	A0A140VJY3

Not detected

Low

Medium

High

Pubmed ID	Year	Title	Citations
11782390	2002	TSP50, a possible protease in human testes, is activated in breast cancer epithelial cells.	14
25811800	2015	Testes-specific protease 50 promotes cell invasion and metastasis by increasing NF-kappaB-dependent matrix metalloproteinase-9 expression.	13
21765952	2011	High expression of testes-specific protease 50 is associated with poor prognosis in colorectal carcinoma.	12
15491742	2004	Localization and expression of TSP50 protein in human and rodent testes.	8
22574111	2012	The threonine protease activity of testes-specific protease 50 (TSP50) is essential for its function in cell proliferation.	7
29361914	2018	Testes-specific protease 50 (TSP50) promotes invasion and metastasis by inducing EMT in gastric cancer.	6
18662669	2008	Differential methylation of TSP50 and mTSP50 genes in different types of human tissues and mouse spermatic cells.	5
20506264	2010	Basic FGF downregulates TSP50 expression via the ERK/Sp1 pathway.	5
25399078	2014	Down-regulation of testes-specific protease 50 induces apoptosis in human laryngocarcinoma HEp2 cells in a NF-κB-mediated pathway.	5
18462069	2008	Identification and characterization of the human testes-specific protease 50 gene promoter.	4

Dessen P

PRSS50 (serine protease 50)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01