PRSS57 (serine protease 57)

2014-11-01  

Identity

HGNC
PRSS57
LOCATION
19p13.3
LOCUSID
400668
ALIAS
NSP4,PRSSL1,UNQ782

Other Information

Locus ID:

NCBI: 400668
HGNC: 31397
Ensembl: ENSG00000185198

Variants:

dbSNP: 400668
ClinVar: 400668
TCGA: ENSG00000185198
COSMIC: PRSS57

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185198ENST00000329267A0A0A0MR61
ENSG00000185198ENST00000613411Q6UWY2

Expression (GTEx)

0
1
2
3
4
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
239041612013NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity.0
251564282014Structures of neutrophil serine protease 4 reveal an unusual mechanism of substrate recognition by a trypsin-fold protease.0

Citation

Dessen P

PRSS57 (serine protease 57)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72319/prss57